Actinomycin III structure

Actinomycin III

TL;DR: Actinomycin III (CAS 1402-50-2) is a chemical compound with molecular formula C60H84N12O16 and molecular weight 1228.61 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-amino-4,6-dimethyl-3-oxo-1-N-[4,7,10,16-tetramethyl-2,5,8,11,14-pentaoxo-3,12-di(propan-2-yl)-1-oxa-4,7,10,13-tetrazacyclohexadec-15-yl]-9-N-[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide

Also Known As: ACTINOMYCIN III, 2-amino-4,6-dimethyl-3-oxo-1-N-[4,7,10,16-tetramethyl-2,5,8,11,14-pentaoxo-3,12-di(propan-2-yl)-1-oxa-4,7,10,13-tetrazacyclohexadec-15-yl]-9-N-[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide, 2-Amino-4,6-dimethyl-3-oxo-N~1~-[4,7,10,16-tetramethyl-2,5,8,11,14-pentaoxo-3,12-di(propan-2-yl)-1-oxa-4,7,10,13-tetraazacyclohexadecan-15-yl]-N~9~-[2,5,9-trimethyl-1,4,7,11,14-pentaoxo-6,13-di(propan-2-yl)hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-10-yl]-3H-phenoxazine-1,9-dicarboxamide

CAS: 1402-50-2
Molecular Formula C60H84N12O16
Molecular Weight 1228.61 g/mol
LogP 0.19304
Topological Polar Surface Area 359.98 Ų
Hydrogen Bond Donors 5
Hydrogen Bond Acceptors 18
Rotatable Bonds 8
Exact Mass 1228.6128
Heavy Atoms 88
Complexity 3323.8013

Chemical Identifiers

CAS Number 1402-50-2
SMILES CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)CN(C(=O)C(NC6=O)C(C)C)C)C)C)C(C)C)C)N)C

Product Overview

Actinomycin III (CAS 1402-50-2), with molecular formula C60H84N12O16 and molecular weight 1228.61 g/mol. IUPAC: 2-amino-4,6-dimethyl-3-oxo-1-N-[4,7,10,16-tetramethyl-2,5,8,11,14-pentaoxo-3,12-di(propan-2-yl)-1-oxa-4,7,10,13-tetrazacyclohexadec-15-yl]-9-N-[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Actinomycin III

XLogP
0.19304
TPSA (Topological Polar Surface Area)
359.98
Hydrogen Bond Donors
5
Hydrogen Bond Acceptors
18
Rotatable Bonds
8
Heavy Atoms
88
Complexity
3323.8013
Exact Mass
1228.6128
Monoisotopic Mass
1228.6128
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Actinomycin III

The XLogP value of 0.19304 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Actinomycin III. The TPSA of 359.98 Ų indicates high polarity, suggesting Actinomycin III may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Actinomycin III has 5 hydrogen bond donor(s) and 18 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Actinomycin III?

The CAS number of Actinomycin III is 1402-50-2.

What is the molecular formula of Actinomycin III?

The molecular formula of Actinomycin III is C60H84N12O16.

What is the molecular weight of Actinomycin III?

The molecular weight of Actinomycin III is 1228.61 g/mol.

Where can I buy Actinomycin III?

You can request a quote for Actinomycin III directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Actinomycin III?

Yes, KEHONG BIO provides custom synthesis services for Actinomycin III and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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