Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)
TL;DR: Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) (CAS 140132-35-0) is a chemical compound with molecular formula C10H12N2O6P+ and molecular weight 287.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
hydroxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]-oxophosphanium
Also Known As: d4T-HP, Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate), [(2S,5R)-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxyphosphinic acid, hydroxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]-oxophosphanium
| Molecular Formula | C10H12N2O6P+ |
|---|---|
| Molecular Weight | 287.04 g/mol |
| LogP | -0.03508 |
| Topological Polar Surface Area | 110.62 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 287.0433 |
| Heavy Atoms | 19 |
| Complexity | 633.64246 |
Chemical Identifiers
| CAS Number | 140132-35-0 |
|---|---|
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C=C[C@H](O2)CO[P+](=O)O |
Product Overview
Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) (CAS 140132-35-0), with molecular formula C10H12N2O6P+ and molecular weight 287.04 g/mol. IUPAC: hydroxy-[[(2S,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dihydrofuran-2-yl]methoxy]-oxophosphanium.
Chemical Property Profile of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)
Property Insights of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)
The XLogP value of -0.03508 indicates that Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 110.62 Ų falls within the moderate polarity range, balancing permeability and solubility for Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate). Following Lipinski's Rule of Five, Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)?
The CAS number of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) is 140132-35-0.
What is the molecular formula of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)?
The molecular formula of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) is C10H12N2O6P+.
What is the molecular weight of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)?
The molecular weight of Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) is 287.04 g/mol.
Where can I buy Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)?
You can request a quote for Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate)?
Yes, KEHONG BIO provides custom synthesis services for Thymidine, 2',3'-didehydro-3'-deoxy-, 5'-(hydrogen phosphonate) and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.