Bleomycin
TL;DR: Bleomycin (CAS 1400-95-9) is a chemical compound with molecular formula C55H84N17O21S3+ and molecular weight 1414.52 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium
Also Known As: bleomycin, Bleocin, Bleomicin, bleomycin a2, Bleomicina
| Molecular Formula | C55H84N17O21S3+ |
|---|---|
| Molecular Weight | 1414.52 g/mol |
| LogP | -7.70358 |
| Topological Polar Surface Area | 627.07 Ų |
| Hydrogen Bond Donors | 20 |
| Hydrogen Bond Acceptors | 31 |
| Rotatable Bonds | 35 |
| Exact Mass | 1414.5189 |
| Heavy Atoms | 96 |
| Complexity | 3280.5442 |
Chemical Identifiers
| CAS Number | 1400-95-9 |
|---|---|
| SMILES | CC1=C(N=C(N=C1N)[C@H](CC(=O)N)NC[C@@H](C(=O)N)N)C(=O)N[C@@H]([C@H](C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)N[C@H](C)[C@H]([C@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O |
Product Overview
Bleomycin (CAS 1400-95-9), with molecular formula C55H84N17O21S3+ and molecular weight 1414.52 g/mol. IUPAC: 3-[[2-[2-[2-[[(2S,3R)-2-[[(2S,3S,4R)-4-[[(2S,3R)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[3-[4-carbamoyloxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxy-2-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]ethyl]-1,3-thiazol-4-yl]-1,3-thiazole-4-carbonyl]amino]propyl-dimethylsulfanium.
Chemical Property Profile of Bleomycin
Property Insights of Bleomycin
The XLogP value of -7.70358 indicates that Bleomycin is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 627.07 Ų indicates high polarity, suggesting Bleomycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bleomycin has 20 hydrogen bond donor(s) and 31 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Bleomycin?
The CAS number of Bleomycin is 1400-95-9.
What is the molecular formula of Bleomycin?
The molecular formula of Bleomycin is C55H84N17O21S3+.
What is the molecular weight of Bleomycin?
The molecular weight of Bleomycin is 1414.52 g/mol.
Where can I buy Bleomycin?
You can request a quote for Bleomycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Bleomycin?
Yes, KEHONG BIO provides custom synthesis services for Bleomycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.