16-Hydroxytriptolide
TL;DR: 16-Hydroxytriptolide (CAS 139713-80-7) is a chemical compound with molecular formula C20H24O7 and molecular weight 376.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(1S,2S,4S,5S,7R,8R,9S,11S,13S)-8-hydroxy-7-[(2S)-1-hydroxypropan-2-yl]-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one
Also Known As: 16-Hydroxytriptolide, (15S)-16-Hydroxytriptolide, Triptolide, 16-hydroxy-, (15S)-, J3.089.107D, 713H807
| Molecular Formula | C20H24O7 |
|---|---|
| Molecular Weight | 376.15 g/mol |
| LogP | -1.0 |
| Topological Polar Surface Area | 104.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 376.1522 |
| Heavy Atoms | 27 |
| Complexity | 838.0 |
Chemical Identifiers
| CAS Number | 139713-80-7 |
|---|---|
| SMILES | C[C@@H](CO)[C@@]12[C@@H](O1)[C@H]3[C@@]4(O3)[C@]5(CCC6=C([C@@H]5C[C@H]7[C@]4([C@@H]2O)O7)COC6=O)C |
| InChIKey | HPTCYMNPHWXVLA-UBBHAYRHSA-N |
Product Overview
16-Hydroxytriptolide (CAS 139713-80-7), with molecular formula C20H24O7 and molecular weight 376.15 g/mol. IUPAC: (1S,2S,4S,5S,7R,8R,9S,11S,13S)-8-hydroxy-7-[(2S)-1-hydroxypropan-2-yl]-1-methyl-3,6,10,16-tetraoxaheptacyclo[11.7.0.02,4.02,9.05,7.09,11.014,18]icos-14(18)-en-17-one.
Chemical Property Profile of 16-Hydroxytriptolide
Property Insights of 16-Hydroxytriptolide
The XLogP value of -1.0 indicates that 16-Hydroxytriptolide is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 16-Hydroxytriptolide. Following Lipinski's Rule of Five, 16-Hydroxytriptolide has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 16-Hydroxytriptolide?
The CAS number of 16-Hydroxytriptolide is 139713-80-7.
What is the molecular formula of 16-Hydroxytriptolide?
The molecular formula of 16-Hydroxytriptolide is C20H24O7.
What is the molecular weight of 16-Hydroxytriptolide?
The molecular weight of 16-Hydroxytriptolide is 376.15 g/mol.
Where can I buy 16-Hydroxytriptolide?
You can request a quote for 16-Hydroxytriptolide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 16-Hydroxytriptolide?
Yes, KEHONG BIO provides custom synthesis services for 16-Hydroxytriptolide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.