16alpha-Hydroxyprednisolone
TL;DR: 16alpha-Hydroxyprednisolone (CAS 13951-70-7) is a chemical compound with molecular formula C21H28O6 and molecular weight 376.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
Also Known As: 16alpha-Hydroxyprednisolone, OH-PRED, 16, A-hydroxy-prednisolone, 16alpha-Hydroxy-prednisonlone
| Molecular Formula | C21H28O6 |
|---|---|
| Molecular Weight | 376.19 g/mol |
| LogP | 1.2 |
| Topological Polar Surface Area | 115.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 376.1886 |
| Heavy Atoms | 27 |
| Complexity | 756.0 |
Chemical Identifiers
| CAS Number | 13951-70-7 |
|---|---|
| SMILES | CC12CC(C3C(C1CC(C2(C(=O)CO)O)O)CCC4=CC(=O)C=CC34C)O |
| InChIKey | SEKYBDYVXDAYPY-UHFFFAOYSA-N |
Product Overview
16alpha-Hydroxyprednisolone (CAS 13951-70-7), with molecular formula C21H28O6 and molecular weight 376.19 g/mol. IUPAC: 11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of 16alpha-Hydroxyprednisolone
Property Insights of 16alpha-Hydroxyprednisolone
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 16alpha-Hydroxyprednisolone. The TPSA of 115.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 16alpha-Hydroxyprednisolone. Following Lipinski's Rule of Five, 16alpha-Hydroxyprednisolone has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 16alpha-Hydroxyprednisolone?
The CAS number of 16alpha-Hydroxyprednisolone is 13951-70-7.
What is the molecular formula of 16alpha-Hydroxyprednisolone?
The molecular formula of 16alpha-Hydroxyprednisolone is C21H28O6.
What is the molecular weight of 16alpha-Hydroxyprednisolone?
The molecular weight of 16alpha-Hydroxyprednisolone is 376.19 g/mol.
Where can I buy 16alpha-Hydroxyprednisolone?
You can request a quote for 16alpha-Hydroxyprednisolone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 16alpha-Hydroxyprednisolone?
Yes, KEHONG BIO provides custom synthesis services for 16alpha-Hydroxyprednisolone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.