Darbufelone mesylate structure

Darbufelone mesylate

TL;DR: Darbufelone mesylate (CAS 139340-56-0) is a chemical compound with molecular formula C19H28N2O5S2 and molecular weight 428.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(5Z)-2-amino-5-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-1,3-thiazol-4-one;methanesulfonic acid

Also Known As: Darbufelone mesylate, Darbufelone mesilate, Darbufelone, Darbufelonemesilate, CI-1004 mesylate

CAS: 139340-56-0
Molecular Formula C19H28N2O5S2
Molecular Weight 428.14 g/mol
LogP 3.4202
Topological Polar Surface Area 130.05 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 6
Rotatable Bonds 1
Exact Mass 428.14395
Heavy Atoms 28
Complexity 891.04626

Chemical Identifiers

CAS Number 139340-56-0
SMILES CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)/C=C\2/C(=O)N=C(S2)N.CS(=O)(=O)O

Product Overview

Darbufelone mesylate (CAS 139340-56-0), with molecular formula C19H28N2O5S2 and molecular weight 428.14 g/mol. IUPAC: (5Z)-2-amino-5-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-1,3-thiazol-4-one;methanesulfonic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of Darbufelone mesylate

XLogP
3.4202
TPSA (Topological Polar Surface Area)
130.05
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
6
Rotatable Bonds
1
Heavy Atoms
28
Complexity
891.04626
Exact Mass
428.14395
Monoisotopic Mass
428.14395
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of Darbufelone mesylate

The XLogP value of 3.4202 indicates that Darbufelone mesylate is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 130.05 Ų falls within the moderate polarity range, balancing permeability and solubility for Darbufelone mesylate. Following Lipinski's Rule of Five, Darbufelone mesylate has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of Darbufelone mesylate?

The CAS number of Darbufelone mesylate is 139340-56-0.

What is the molecular formula of Darbufelone mesylate?

The molecular formula of Darbufelone mesylate is C19H28N2O5S2.

What is the molecular weight of Darbufelone mesylate?

The molecular weight of Darbufelone mesylate is 428.14 g/mol.

Where can I buy Darbufelone mesylate?

You can request a quote for Darbufelone mesylate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for Darbufelone mesylate?

Yes, KEHONG BIO provides custom synthesis services for Darbufelone mesylate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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