RG 14620
TL;DR: RG 14620 (CAS 138989-57-8) is a chemical compound with molecular formula C14H8Cl2N2 and molecular weight 274.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(Z)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile
Also Known As: Tyrphostin RG 14620, Tyrphostin RG-14620, Tyrphostin RG14620, BiomolKI2_000020, RG 14620
| Molecular Formula | C14H8Cl2N2 |
|---|---|
| Molecular Weight | 274.01 g/mol |
| LogP | 4.45258 |
| Topological Polar Surface Area | 36.68 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 274.00644 |
| Heavy Atoms | 18 |
| Complexity | 607.7374 |
Chemical Identifiers
| CAS Number | 138989-57-8 |
|---|---|
| SMILES | C1=CC(=CN=C1)/C(=C/C2=CC(=CC(=C2)Cl)Cl)/C#N |
Product Overview
RG 14620 (CAS 138989-57-8), with molecular formula C14H8Cl2N2 and molecular weight 274.01 g/mol. IUPAC: (Z)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile.
Chemical Property Profile of RG 14620
Property Insights of RG 14620
The XLogP value of 4.45258 indicates that RG 14620 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.68 Ų, RG 14620 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RG 14620 has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RG 14620?
The CAS number of RG 14620 is 138989-57-8.
What is the molecular formula of RG 14620?
The molecular formula of RG 14620 is C14H8Cl2N2.
What is the molecular weight of RG 14620?
The molecular weight of RG 14620 is 274.01 g/mol.
Where can I buy RG 14620?
You can request a quote for RG 14620 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RG 14620?
Yes, KEHONG BIO provides custom synthesis services for RG 14620 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.