Capsazepine
TL;DR: Capsazepine (CAS 138977-28-3) is a chemical compound with molecular formula C19H21ClN2O2S and molecular weight 376.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
Also Known As: capsazepine, capsazepin, capasazepine, casZ, Capasazepine?
| Molecular Formula | C19H21ClN2O2S |
|---|---|
| Molecular Weight | 376.10 g/mol |
| LogP | 3.6166 |
| Topological Polar Surface Area | 55.73 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 376.10123 |
| Heavy Atoms | 25 |
| Complexity | 764.7646 |
Chemical Identifiers
| CAS Number | 138977-28-3 |
|---|---|
| SMILES | C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O |
Product Overview
Capsazepine (CAS 138977-28-3), with molecular formula C19H21ClN2O2S and molecular weight 376.10 g/mol. IUPAC: N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide.
Chemical Property Profile of Capsazepine
Property Insights of Capsazepine
The XLogP value of 3.6166 indicates that Capsazepine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.73 Ų, Capsazepine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Capsazepine has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Capsazepine?
The CAS number of Capsazepine is 138977-28-3.
What is the molecular formula of Capsazepine?
The molecular formula of Capsazepine is C19H21ClN2O2S.
What is the molecular weight of Capsazepine?
The molecular weight of Capsazepine is 376.10 g/mol.
Where can I buy Capsazepine?
You can request a quote for Capsazepine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Capsazepine?
Yes, KEHONG BIO provides custom synthesis services for Capsazepine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.