ADR-851 free base structure

ADR-851 free base

TL;DR: ADR-851 free base (CAS 138559-56-5) is a chemical compound with molecular formula C14H18ClN3O2 and molecular weight 295.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-amino-5-chloro-N-[[(2S)-pyrrolidin-2-yl]methyl]-2,3-dihydro-1-benzofuran-7-carboxamide

Also Known As: ADR-851 free base, Adr 851, ADR 851 (free base), 7-Benzofurancarboxamide, 4-amino-5-chloro-2,3-dihydro-N-(2-pyrrolidinylmethyl)-, (S)-, 4-amino-5-chloro-N-[[(2S)-pyrrolidin-2-yl]methyl]-2,3-dihydro-1-benzofuran-7-carboxamide

CAS: 138559-56-5
Molecular Formula C14H18ClN3O2
Molecular Weight 295.11 g/mol
LogP 1.3
Topological Polar Surface Area 76.4 Ų
Hydrogen Bond Donors 3
Hydrogen Bond Acceptors 4
Rotatable Bonds 3
Exact Mass 295.10876
Heavy Atoms 20
Complexity 368.0

Chemical Identifiers

CAS Number 138559-56-5
SMILES C1C[C@H](NC1)CNC(=O)C2=CC(=C(C3=C2OCC3)N)Cl
InChIKey MPECLPSCJHXWNO-QMMMGPOBSA-N

Patent-Derived Application Labels

Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.

Pharmaceutical Intermediates (7 patents)

Product Overview

ADR-851 free base (CAS 138559-56-5), with molecular formula C14H18ClN3O2 and molecular weight 295.11 g/mol. IUPAC: 4-amino-5-chloro-N-[[(2S)-pyrrolidin-2-yl]methyl]-2,3-dihydro-1-benzofuran-7-carboxamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of ADR-851 free base

XLogP
1.3
TPSA (Topological Polar Surface Area)
76.4
Hydrogen Bond Donors
3
Hydrogen Bond Acceptors
4
Rotatable Bonds
3
Heavy Atoms
20
Complexity
368.0
Exact Mass
295.10876
Monoisotopic Mass
295.10876
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of ADR-851 free base

The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for ADR-851 free base. The TPSA of 76.4 Ų falls within the moderate polarity range, balancing permeability and solubility for ADR-851 free base. Following Lipinski's Rule of Five, ADR-851 free base has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of ADR-851 free base?

The CAS number of ADR-851 free base is 138559-56-5.

What is the molecular formula of ADR-851 free base?

The molecular formula of ADR-851 free base is C14H18ClN3O2.

What is the molecular weight of ADR-851 free base?

The molecular weight of ADR-851 free base is 295.11 g/mol.

Where can I buy ADR-851 free base?

You can request a quote for ADR-851 free base directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for ADR-851 free base?

Yes, KEHONG BIO provides custom synthesis services for ADR-851 free base and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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