Sdz 214-103
TL;DR: Sdz 214-103 (CAS 138240-77-4) is a chemical compound with molecular formula C64H114N10O14 and molecular weight 1246.85 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S,6S,9S,12S,18S,24S,27S,30S,33R)-18-[(1R)-1-hydroxyethyl]-21-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-3,7,13,16,22,25,31-heptamethyl-6,9,12,27,30-pentakis(2-methylpropyl)-24,33-di(propan-2-yl)-1-oxa-4,7,10,13,16,19,22,25,28,31-decazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone
Also Known As: Sdz 214-103, sdz-214-103, Cyclosporin, thr(2)-leu(5)-hiv(8)-leu(10)-, 2-Thr-5-leu-8-hiv-10-leu-cyclosporin, Cyclosporin, threonyl(2)-leucyl(5)-2-hydroxyisovalyl(8)-leucine(10)-
| Molecular Formula | C64H114N10O14 |
|---|---|
| Molecular Weight | 1246.85 g/mol |
| LogP | 3.3508 |
| Topological Polar Surface Area | 305.02 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 17 |
| Exact Mass | 1246.8516 |
| Heavy Atoms | 88 |
| Complexity | 2394.463 |
Chemical Identifiers
| CAS Number | 138240-77-4 |
|---|---|
| SMILES | C/C=C/C[C@@H](C)[C@H](C1C(=O)N[C@H](C(=O)N(CC(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)O[C@@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)CC(C)C)C)C(C)C)C)CC(C)C)C)CC(C)C)CC(C)C)C)C)[C@@H](C)O)O |
Product Overview
Sdz 214-103 (CAS 138240-77-4), with molecular formula C64H114N10O14 and molecular weight 1246.85 g/mol. IUPAC: (3S,6S,9S,12S,18S,24S,27S,30S,33R)-18-[(1R)-1-hydroxyethyl]-21-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-3,7,13,16,22,25,31-heptamethyl-6,9,12,27,30-pentakis(2-methylpropyl)-24,33-di(propan-2-yl)-1-oxa-4,7,10,13,16,19,22,25,28,31-decazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone.
Chemical Property Profile of Sdz 214-103
Property Insights of Sdz 214-103
The XLogP value of 3.3508 indicates that Sdz 214-103 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 305.02 Ų indicates high polarity, suggesting Sdz 214-103 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Sdz 214-103 has 6 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Sdz 214-103?
The CAS number of Sdz 214-103 is 138240-77-4.
What is the molecular formula of Sdz 214-103?
The molecular formula of Sdz 214-103 is C64H114N10O14.
What is the molecular weight of Sdz 214-103?
The molecular weight of Sdz 214-103 is 1246.85 g/mol.
Where can I buy Sdz 214-103?
You can request a quote for Sdz 214-103 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Sdz 214-103?
Yes, KEHONG BIO provides custom synthesis services for Sdz 214-103 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.