9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine
TL;DR: 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine (CAS 137819-73-9) is a chemical compound with molecular formula C10H11ClN4OS and molecular weight 270.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2S,5R)-5-(6-chloropurin-9-yl)thiolan-2-yl]methanol
Also Known As: 4-Thionucleoside analog, 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine, [(2S,5R)-5-(6-chloropurin-9-yl)thiolan-2-yl]methanol, [(2S,5R)-5-(6-Chloro-9H-purin-9-yl)thiolan-2-yl]methanol, [(2S,5R)-5-(6-chloropurin-9-yl)tetrahydrothiophen-2-yl]methanol
| Molecular Formula | C10H11ClN4OS |
|---|---|
| Molecular Weight | 270.03 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 89.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 270.0342 |
| Heavy Atoms | 17 |
| Complexity | 285.0 |
Chemical Identifiers
| CAS Number | 137819-73-9 |
|---|---|
| SMILES | C1C[C@@H](S[C@@H]1CO)N2C=NC3=C2N=CN=C3Cl |
| InChIKey | FVTOAGYDCTXLRX-NKWVEPMBSA-N |
Product Overview
9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine (CAS 137819-73-9), with molecular formula C10H11ClN4OS and molecular weight 270.03 g/mol. IUPAC: [(2S,5R)-5-(6-chloropurin-9-yl)thiolan-2-yl]methanol.
Chemical Property Profile of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine
Property Insights of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine. The TPSA of 89.1 Ų falls within the moderate polarity range, balancing permeability and solubility for 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine. Following Lipinski's Rule of Five, 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine?
The CAS number of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine is 137819-73-9.
What is the molecular formula of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine?
The molecular formula of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine is C10H11ClN4OS.
What is the molecular weight of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine?
The molecular weight of 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine is 270.03 g/mol.
Where can I buy 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine?
You can request a quote for 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine?
Yes, KEHONG BIO provides custom synthesis services for 9-(2,3-Dideoxy-4-thio-alpha,beta-D-ribofuranosyl)-6-chloropurine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.