Spiroglumide
TL;DR: Spiroglumide (CAS 137795-35-8) is a chemical compound with molecular formula C21H26Cl2N2O4 and molecular weight 440.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4R)-5-(8-azaspiro[4.5]decan-8-yl)-4-[(3,5-dichlorobenzoyl)amino]-5-oxopentanoic acid
Also Known As: Spiroglumide, Saterinone, espiroglumida, Radaxafine HCl, spiroglumidum
| Molecular Formula | C21H26Cl2N2O4 |
|---|---|
| Molecular Weight | 440.13 g/mol |
| LogP | 4.4 |
| Topological Polar Surface Area | 86.7 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 440.12695 |
| Heavy Atoms | 29 |
| Complexity | 604.0 |
Chemical Identifiers
| CAS Number | 137795-35-8 |
|---|---|
| SMILES | C1CCC2(C1)CCN(CC2)C(=O)[C@@H](CCC(=O)O)NC(=O)C3=CC(=CC(=C3)Cl)Cl |
| InChIKey | FJCZHMXAGBYXHJ-QGZVFWFLSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Spiroglumide (CAS 137795-35-8), with molecular formula C21H26Cl2N2O4 and molecular weight 440.13 g/mol. IUPAC: (4R)-5-(8-azaspiro[4.5]decan-8-yl)-4-[(3,5-dichlorobenzoyl)amino]-5-oxopentanoic acid.
Chemical Property Profile of Spiroglumide
Property Insights of Spiroglumide
The XLogP value of 4.4 indicates that Spiroglumide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.7 Ų falls within the moderate polarity range, balancing permeability and solubility for Spiroglumide. Following Lipinski's Rule of Five, Spiroglumide has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Spiroglumide?
The CAS number of Spiroglumide is 137795-35-8.
What is the molecular formula of Spiroglumide?
The molecular formula of Spiroglumide is C21H26Cl2N2O4.
What is the molecular weight of Spiroglumide?
The molecular weight of Spiroglumide is 440.13 g/mol.
Where can I buy Spiroglumide?
You can request a quote for Spiroglumide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Spiroglumide?
Yes, KEHONG BIO provides custom synthesis services for Spiroglumide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.