2-hydroxyglutaryl-5-coenzyme A structure

2-hydroxyglutaryl-5-coenzyme A

TL;DR: 2-hydroxyglutaryl-5-coenzyme A (CAS 137374-53-9) is a chemical compound with molecular formula C26H42N7O20P3S and molecular weight 897.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

5-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-2-hydroxy-5-oxopentanoic acid

Also Known As: 2-Hydroxyglutaryl-5-coa, 2-Hydroxyglutaryl-5-coenzyme A, 5-Coenzyme A, 2-hydroxyglutaryl, 5-CoenzymeA,2-hydroxyglutaryl, (R)-2-Hydroxyglutaryl-5-CoA

CAS: 137374-53-9
Molecular Formula C26H42N7O20P3S
Molecular Weight 897.14 g/mol
LogP -2.1096
Topological Polar Surface Area 421.16 Ų
Hydrogen Bond Donors 11
Hydrogen Bond Acceptors 20
Rotatable Bonds 23
Exact Mass 897.14185
Heavy Atoms 57
Complexity 1899.6998

Chemical Identifiers

CAS Number 137374-53-9
SMILES CC(C)(COP(=O)(O)OP(=O)(O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)[C@H](C(=O)NCCC(=O)NCCSC(=O)CCC(C(=O)O)O)O

Product Overview

2-hydroxyglutaryl-5-coenzyme A (CAS 137374-53-9), with molecular formula C26H42N7O20P3S and molecular weight 897.14 g/mol. IUPAC: 5-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethylsulfanyl]-2-hydroxy-5-oxopentanoic acid.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 2-hydroxyglutaryl-5-coenzyme A

XLogP
-2.1096
TPSA (Topological Polar Surface Area)
421.16
Hydrogen Bond Donors
11
Hydrogen Bond Acceptors
20
Rotatable Bonds
23
Heavy Atoms
57
Complexity
1899.6998
Exact Mass
897.14185
Monoisotopic Mass
897.14185
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 2-hydroxyglutaryl-5-coenzyme A

The XLogP value of -2.1096 indicates that 2-hydroxyglutaryl-5-coenzyme A is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 421.16 Ų indicates high polarity, suggesting 2-hydroxyglutaryl-5-coenzyme A may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-hydroxyglutaryl-5-coenzyme A has 11 hydrogen bond donor(s) and 20 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 2-hydroxyglutaryl-5-coenzyme A?

The CAS number of 2-hydroxyglutaryl-5-coenzyme A is 137374-53-9.

What is the molecular formula of 2-hydroxyglutaryl-5-coenzyme A?

The molecular formula of 2-hydroxyglutaryl-5-coenzyme A is C26H42N7O20P3S.

What is the molecular weight of 2-hydroxyglutaryl-5-coenzyme A?

The molecular weight of 2-hydroxyglutaryl-5-coenzyme A is 897.14 g/mol.

Where can I buy 2-hydroxyglutaryl-5-coenzyme A?

You can request a quote for 2-hydroxyglutaryl-5-coenzyme A directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 2-hydroxyglutaryl-5-coenzyme A?

Yes, KEHONG BIO provides custom synthesis services for 2-hydroxyglutaryl-5-coenzyme A and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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