DOTAEt structure

DOTAEt

TL;DR: DOTAEt (CAS 137076-50-7) is a chemical compound with molecular formula C24H44N4O8 and molecular weight 516.32 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 2-[4,7,10-tris(2-ethoxy-2-oxoethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate

Also Known As: DOTAEt, Gadobutrol Impurity 143, 1,4,7,10-TETRAKIS(ETHOXYCARBONYLMETHYL)-1,4,7,10-TETRAAZACYCLODODECANE, ethyl 2-[4,7,10-tris(2-ethoxy-2-oxoethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate, 1,4,7,10-Tetrakis -1,4,7,10-tetraazacyclododecane

CAS: 137076-50-7
Molecular Formula C24H44N4O8
Molecular Weight 516.32 g/mol
LogP -0.5396
Topological Polar Surface Area 118.16 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 12
Rotatable Bonds 12
Exact Mass 516.3159
Heavy Atoms 36
Complexity 550.50195

Chemical Identifiers

CAS Number 137076-50-7
SMILES CCOC(=O)CN1CCN(CCN(CCN(CC1)CC(=O)OCC)CC(=O)OCC)CC(=O)OCC

Product Overview

DOTAEt (CAS 137076-50-7), with molecular formula C24H44N4O8 and molecular weight 516.32 g/mol. IUPAC: ethyl 2-[4,7,10-tris(2-ethoxy-2-oxoethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of DOTAEt

XLogP
-0.5396
TPSA (Topological Polar Surface Area)
118.16
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
12
Rotatable Bonds
12
Heavy Atoms
36
Complexity
550.50195
Exact Mass
516.3159
Monoisotopic Mass
516.3159
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of DOTAEt

The XLogP value of -0.5396 indicates that DOTAEt is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 118.16 Ų falls within the moderate polarity range, balancing permeability and solubility for DOTAEt. Following Lipinski's Rule of Five, DOTAEt has 0 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of DOTAEt?

The CAS number of DOTAEt is 137076-50-7.

What is the molecular formula of DOTAEt?

The molecular formula of DOTAEt is C24H44N4O8.

What is the molecular weight of DOTAEt?

The molecular weight of DOTAEt is 516.32 g/mol.

Where can I buy DOTAEt?

You can request a quote for DOTAEt directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for DOTAEt?

Yes, KEHONG BIO provides custom synthesis services for DOTAEt and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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