B 1548
TL;DR: B 1548 (CAS 136996-83-3) is a chemical compound with molecular formula C17H23Cl2N3O2S and molecular weight 403.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(4-methyl-1,3-thiazol-5-yl)oxy]propan-2-ol;hydrochloride
Also Known As: B 1548, 1-Piperazineethanol, 4-(3-chlorophenyl)-alpha-(((4-methyl-5-thiazolyl)oxy)methyl)-, monohydrochloride, 3-(4-m-Chlorophenylpiperazin-1-yl)-1-(4-methylthiazolyl-5-oxy)propan-2-ol hydrochloride, 1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(4-methyl-1,3-thiazol-5-yl)oxy]propan-2-ol hydrochloride, 1-[4-(3-Chlorophenyl)piperazin-1-yl]-3-[(4-methyl-1,3-thiazol-5-yl)oxy]propan-2-ol--hydrogen chloride (1/1)
| Molecular Formula | C17H23Cl2N3O2S |
|---|---|
| Molecular Weight | 403.09 g/mol |
| LogP | 3.08862 |
| Topological Polar Surface Area | 48.83 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 403.0888 |
| Heavy Atoms | 25 |
| Complexity | 662.8475 |
Chemical Identifiers
| CAS Number | 136996-83-3 |
|---|---|
| SMILES | CC1=C(SC=N1)OCC(CN2CCN(CC2)C3=CC(=CC=C3)Cl)O.Cl |
Product Overview
B 1548 (CAS 136996-83-3), with molecular formula C17H23Cl2N3O2S and molecular weight 403.09 g/mol. IUPAC: 1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(4-methyl-1,3-thiazol-5-yl)oxy]propan-2-ol;hydrochloride.
Chemical Property Profile of B 1548
Property Insights of B 1548
The XLogP value of 3.08862 indicates that B 1548 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 48.83 Ų, B 1548 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, B 1548 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of B 1548?
The CAS number of B 1548 is 136996-83-3.
What is the molecular formula of B 1548?
The molecular formula of B 1548 is C17H23Cl2N3O2S.
What is the molecular weight of B 1548?
The molecular weight of B 1548 is 403.09 g/mol.
Where can I buy B 1548?
You can request a quote for B 1548 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for B 1548?
Yes, KEHONG BIO provides custom synthesis services for B 1548 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.