Foropafant
TL;DR: Foropafant (CAS 136468-36-5) is a chemical compound with molecular formula C28H40N4S and molecular weight 464.30 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N,N-dimethyl-N'-(pyridin-3-ylmethyl)-N'-[4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl]ethane-1,2-diamine
Also Known As: Foropafant, foropafantum, Foropafant [INN], N1,N1-Dimethyl-N2-(pyridin-3-ylmethyl)-N2-(4-(2,4,6-triisopropylphenyl)thiazol-2-yl)ethane-1,2-diamine, Foropafant < Prop INN >
| Molecular Formula | C28H40N4S |
|---|---|
| Molecular Weight | 464.30 g/mol |
| LogP | 6.9 |
| Topological Polar Surface Area | 60.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 10 |
| Exact Mass | 464.29736 |
| Heavy Atoms | 33 |
| Complexity | 548.0 |
Chemical Identifiers
| CAS Number | 136468-36-5 |
|---|---|
| SMILES | CC(C)C1=CC(=C(C(=C1)C(C)C)C2=CSC(=N2)N(CCN(C)C)CC3=CN=CC=C3)C(C)C |
| InChIKey | VVBFISAUNSXQGZ-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Foropafant (CAS 136468-36-5), with molecular formula C28H40N4S and molecular weight 464.30 g/mol. IUPAC: N,N-dimethyl-N'-(pyridin-3-ylmethyl)-N'-[4-[2,4,6-tri(propan-2-yl)phenyl]-1,3-thiazol-2-yl]ethane-1,2-diamine.
Chemical Property Profile of Foropafant
Property Insights of Foropafant
The XLogP value of 6.9 indicates that Foropafant is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.5 Ų falls within the moderate polarity range, balancing permeability and solubility for Foropafant. Following Lipinski's Rule of Five, Foropafant has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Foropafant?
The CAS number of Foropafant is 136468-36-5.
What is the molecular formula of Foropafant?
The molecular formula of Foropafant is C28H40N4S.
What is the molecular weight of Foropafant?
The molecular weight of Foropafant is 464.30 g/mol.
Where can I buy Foropafant?
You can request a quote for Foropafant directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Foropafant?
Yes, KEHONG BIO provides custom synthesis services for Foropafant and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.