RefChem:209045
TL;DR: RefChem:209045 (CAS 136379-65-2) is a chemical compound with molecular formula C18H34O3Si and molecular weight 326.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(4aR,5R,8R,8aR)-5-[tert-butyl(dimethyl)silyl]oxy-8-hydroxy-4a,8-dimethyl-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-one
Also Known As: (4aR,5R,8R,8aR)-5-(tert-Butyl-dimethylsilyl)oxy-8-hydroxy-4a,8-dimethyl-3,4,5,6,7,8a-?hexahydro-1H-naphthalen-2-one, (4aR,5R,8R,8aR)-5-[tert-butyl(dimethyl)silyl]oxy-8-hydroxy-4a,8-dimethyl-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-one, 5-{[tert-Butyl(dimethyl)silyl]oxy}-8-hydroxy-4a,8-dimethyloctahydronaphthalen-2(1H)-one, (4aR,5R,8R,8aR)-5-{[tert-Butyldi(methyl)silyl]oxy}-8-hydroxy-4a,8-dimethyloctahydronaphthalen-2(1H)-one, RefChem:209045
| Molecular Formula | C18H34O3Si |
|---|---|
| Molecular Weight | 326.23 g/mol |
| LogP | 4.2971 |
| Topological Polar Surface Area | 46.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 326.22772 |
| Heavy Atoms | 22 |
| Complexity | 454.0 |
Chemical Identifiers
| CAS Number | 136379-65-2 |
|---|---|
| SMILES | C[C@@]12CCC(=O)C[C@H]1[C@](CC[C@H]2O[Si](C)(C)C(C)(C)C)(C)O |
| InChIKey | GOINRXRILMBUAT-JOCBIADPSA-N |
Product Overview
RefChem:209045 (CAS 136379-65-2), with molecular formula C18H34O3Si and molecular weight 326.23 g/mol. IUPAC: (4aR,5R,8R,8aR)-5-[tert-butyl(dimethyl)silyl]oxy-8-hydroxy-4a,8-dimethyl-3,4,5,6,7,8a-hexahydro-1H-naphthalen-2-one.
Chemical Property Profile of RefChem:209045
Property Insights of RefChem:209045
The XLogP value of 4.2971 indicates that RefChem:209045 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.5 Ų, RefChem:209045 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, RefChem:209045 has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of RefChem:209045?
The CAS number of RefChem:209045 is 136379-65-2.
What is the molecular formula of RefChem:209045?
The molecular formula of RefChem:209045 is C18H34O3Si.
What is the molecular weight of RefChem:209045?
The molecular weight of RefChem:209045 is 326.23 g/mol.
Where can I buy RefChem:209045?
You can request a quote for RefChem:209045 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for RefChem:209045?
Yes, KEHONG BIO provides custom synthesis services for RefChem:209045 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.