41-Oxo-rapamycin structure

41-Oxo-rapamycin

TL;DR: 41-Oxo-rapamycin (CAS 136293-03-3) is a chemical compound with molecular formula C51H77NO13 and molecular weight 911.54 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-12-[(2R)-1-[(1S,3R)-3-methoxy-4-oxocyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

Also Known As: 41-Oxo-rapamycin

CAS: 136293-03-3
Molecular Formula C51H77NO13
Molecular Weight 911.54 g/mol
LogP 6.3888
Topological Polar Surface Area 192.27 Ų
Hydrogen Bond Donors 2
Hydrogen Bond Acceptors 13
Rotatable Bonds 6
Exact Mass 911.5395
Heavy Atoms 65
Complexity 1802.0544

Chemical Identifiers

CAS Number 136293-03-3
SMILES C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CCC(=O)[C@@H](C4)OC)C)/C)O)OC)C)C)/C)OC

Product Overview

41-Oxo-rapamycin (CAS 136293-03-3), with molecular formula C51H77NO13 and molecular weight 911.54 g/mol. IUPAC: (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-12-[(2R)-1-[(1S,3R)-3-methoxy-4-oxocyclohexyl]propan-2-yl]-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 41-Oxo-rapamycin

XLogP
6.3888
TPSA (Topological Polar Surface Area)
192.27
Hydrogen Bond Donors
2
Hydrogen Bond Acceptors
13
Rotatable Bonds
6
Heavy Atoms
65
Complexity
1802.0544
Exact Mass
911.5395
Monoisotopic Mass
911.5395
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 41-Oxo-rapamycin

The XLogP value of 6.3888 indicates that 41-Oxo-rapamycin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 192.27 Ų indicates high polarity, suggesting 41-Oxo-rapamycin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 41-Oxo-rapamycin has 2 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 41-Oxo-rapamycin?

The CAS number of 41-Oxo-rapamycin is 136293-03-3.

What is the molecular formula of 41-Oxo-rapamycin?

The molecular formula of 41-Oxo-rapamycin is C51H77NO13.

What is the molecular weight of 41-Oxo-rapamycin?

The molecular weight of 41-Oxo-rapamycin is 911.54 g/mol.

Where can I buy 41-Oxo-rapamycin?

You can request a quote for 41-Oxo-rapamycin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 41-Oxo-rapamycin?

Yes, KEHONG BIO provides custom synthesis services for 41-Oxo-rapamycin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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