4-Phenyl-5-(trifluoromethyl)thiophen-3-amine
TL;DR: 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine (CAS 136222-47-4) is a chemical compound with molecular formula C11H8F3NS and molecular weight 243.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-phenyl-5-(trifluoromethyl)thiophen-3-amine
Also Known As: 4-phenyl-5-(trifluoromethyl)thiophen-3-amine, Maybridge3_006438, 3-Amino-4-phenyl-5-(trifluoromethyl)thiophene, 4-Phenyl-5-(trifluoromethyl)thien-3-ylamine, 8507AD
| Molecular Formula | C11H8F3NS |
|---|---|
| Molecular Weight | 243.03 g/mol |
| LogP | 4.0161 |
| Topological Polar Surface Area | 26.02 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 243.03296 |
| Heavy Atoms | 16 |
| Complexity | 487.67593 |
Chemical Identifiers
| CAS Number | 136222-47-4 |
|---|---|
| SMILES | C1=CC=C(C=C1)C2=C(SC=C2N)C(F)(F)F |
Product Overview
4-Phenyl-5-(trifluoromethyl)thiophen-3-amine (CAS 136222-47-4), with molecular formula C11H8F3NS and molecular weight 243.03 g/mol. IUPAC: 4-phenyl-5-(trifluoromethyl)thiophen-3-amine.
Chemical Property Profile of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine
Property Insights of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine
The XLogP value of 4.0161 indicates that 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 26.02 Ų, 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine?
The CAS number of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine is 136222-47-4.
What is the molecular formula of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine?
The molecular formula of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine is C11H8F3NS.
What is the molecular weight of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine?
The molecular weight of 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine is 243.03 g/mol.
Where can I buy 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine?
You can request a quote for 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine?
Yes, KEHONG BIO provides custom synthesis services for 4-Phenyl-5-(trifluoromethyl)thiophen-3-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.