24-fluoro-1,25-dihydroxyvitaminD2
TL;DR: 24-fluoro-1,25-dihydroxyvitaminD2 (CAS 135776-86-2) is a chemical compound with molecular formula C28H43FO3 and molecular weight 446.32 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5-fluoro-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
Also Known As: 24-fluoro-1,25-dihydroxyvitaminD2, (24R)-24-Fluoro-1alpha,25-dihydroxyergocalciferol, (24R)-24-fluoro-1alpha,25-dihydroxyvitamin D2 / (24R)-24-fluoro-1alpha,25-dihydroxyergocalciferol, (5Z,7E,22E)-(1S,3R,24R)-24-fluoro-9,10-seco-5,7,10(19),22-ergostatetraene-1,3,25-triol, (1R,3S,5Z)-5-{2-[(1R,3aS,4E,7aR)-1-[(2R,3E,5R)-5-fluoro-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexane-1,3-diol
| Molecular Formula | C28H43FO3 |
|---|---|
| Molecular Weight | 446.32 g/mol |
| LogP | 5.8188 |
| Topological Polar Surface Area | 60.69 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 446.3196 |
| Heavy Atoms | 32 |
| Complexity | 799.98535 |
Chemical Identifiers
| CAS Number | 135776-86-2 |
|---|---|
| SMILES | C[C@H](/C=C/[C@](C)(C(C)(C)O)F)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](C[C@@H](C3=C)O)O)C |
Product Overview
24-fluoro-1,25-dihydroxyvitaminD2 (CAS 135776-86-2), with molecular formula C28H43FO3 and molecular weight 446.32 g/mol. IUPAC: trans-(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(E,2R,5R)-5-fluoro-6-hydroxy-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol.
Chemical Property Profile of 24-fluoro-1,25-dihydroxyvitaminD2
Property Insights of 24-fluoro-1,25-dihydroxyvitaminD2
The XLogP value of 5.8188 indicates that 24-fluoro-1,25-dihydroxyvitaminD2 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.69 Ų falls within the moderate polarity range, balancing permeability and solubility for 24-fluoro-1,25-dihydroxyvitaminD2. Following Lipinski's Rule of Five, 24-fluoro-1,25-dihydroxyvitaminD2 has 3 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 24-fluoro-1,25-dihydroxyvitaminD2?
The CAS number of 24-fluoro-1,25-dihydroxyvitaminD2 is 135776-86-2.
What is the molecular formula of 24-fluoro-1,25-dihydroxyvitaminD2?
The molecular formula of 24-fluoro-1,25-dihydroxyvitaminD2 is C28H43FO3.
What is the molecular weight of 24-fluoro-1,25-dihydroxyvitaminD2?
The molecular weight of 24-fluoro-1,25-dihydroxyvitaminD2 is 446.32 g/mol.
Where can I buy 24-fluoro-1,25-dihydroxyvitaminD2?
You can request a quote for 24-fluoro-1,25-dihydroxyvitaminD2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 24-fluoro-1,25-dihydroxyvitaminD2?
Yes, KEHONG BIO provides custom synthesis services for 24-fluoro-1,25-dihydroxyvitaminD2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.