Men 10376
TL;DR: Men 10376 (CAS 135306-85-3) is a chemical compound with molecular formula C57H68N12O10 and molecular weight 1080.52 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3S)-3-amino-4-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Also Known As: Men 10376, MEN-10,376, Neurokinin-2 receptor antagonist, H-Asp-Tyr-D-Trp-Val-D-Trp-D-Trp-Lys-NH2, neurokinin A(4-10), Tyr(5)-Trp(6,8,9)-Lys(10)-
| Molecular Formula | C57H68N12O10 |
|---|---|
| Molecular Weight | 1080.52 g/mol |
| LogP | 1.1 |
| Topological Polar Surface Area | 375.0 Ų |
| Hydrogen Bond Donors | 14 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 28 |
| Exact Mass | 1080.5182 |
| Heavy Atoms | 79 |
| Complexity | 2080.0 |
Chemical Identifiers
| CAS Number | 135306-85-3 |
|---|---|
| SMILES | CC(C)[C@@H](C(=O)N[C@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@H](CC3=CNC4=CC=CC=C43)C(=O)N[C@@H](CCCCN)C(=O)N)NC(=O)[C@@H](CC5=CNC6=CC=CC=C65)NC(=O)[C@H](CC7=CC=C(C=C7)O)NC(=O)[C@H](CC(=O)O)N |
| InChIKey | QQHOFZNACVKNHK-SXVLBCBNSA-N |
Product Overview
Men 10376 (CAS 135306-85-3), with molecular formula C57H68N12O10 and molecular weight 1080.52 g/mol. IUPAC: (3S)-3-amino-4-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2R)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-oxobutanoic acid.
Chemical Property Profile of Men 10376
Property Insights of Men 10376
The XLogP value of 1.1 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Men 10376. The TPSA of 375.0 Ų indicates high polarity, suggesting Men 10376 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Men 10376 has 14 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Men 10376?
The CAS number of Men 10376 is 135306-85-3.
What is the molecular formula of Men 10376?
The molecular formula of Men 10376 is C57H68N12O10.
What is the molecular weight of Men 10376?
The molecular weight of Men 10376 is 1080.52 g/mol.
Where can I buy Men 10376?
You can request a quote for Men 10376 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Men 10376?
Yes, KEHONG BIO provides custom synthesis services for Men 10376 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.