Manifaxine hydrochloride
TL;DR: Manifaxine hydrochloride (CAS 135306-42-2) is a chemical compound with molecular formula C12H16ClF2NO2 and molecular weight 279.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethylmorpholin-2-ol;hydrochloride
Also Known As: Manifaxine hydrochloride, BW-1555U88, (2R,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethyl-morpholin-2-ol Hydrochloride, (2S,3S,5R)-2-(3,5-difluorophenyl)-3 5-dimethyl-2-morpholinol hydrochloride, 2-(3,5-Difluorophenyl)-3,5-dimethyl-(2S-(2a,3a,5a))-2-morpholinol hydrochloride
| Molecular Formula | C12H16ClF2NO2 |
|---|---|
| Molecular Weight | 279.08 g/mol |
| LogP | 1.9285 |
| Topological Polar Surface Area | 41.49 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 279.08377 |
| Heavy Atoms | 18 |
| Complexity | 412.28848 |
Chemical Identifiers
| CAS Number | 135306-42-2 |
|---|---|
| SMILES | C[C@@H]1CO[C@]([C@@H](N1)C)(C2=CC(=CC(=C2)F)F)O.Cl |
Product Overview
Manifaxine hydrochloride (CAS 135306-42-2), with molecular formula C12H16ClF2NO2 and molecular weight 279.08 g/mol. IUPAC: (2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethylmorpholin-2-ol;hydrochloride.
Chemical Property Profile of Manifaxine hydrochloride
Property Insights of Manifaxine hydrochloride
The XLogP value of 1.9285 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Manifaxine hydrochloride. With a topological polar surface area (TPSA) of 41.49 Ų, Manifaxine hydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Manifaxine hydrochloride has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Manifaxine hydrochloride?
The CAS number of Manifaxine hydrochloride is 135306-42-2.
What is the molecular formula of Manifaxine hydrochloride?
The molecular formula of Manifaxine hydrochloride is C12H16ClF2NO2.
What is the molecular weight of Manifaxine hydrochloride?
The molecular weight of Manifaxine hydrochloride is 279.08 g/mol.
Where can I buy Manifaxine hydrochloride?
You can request a quote for Manifaxine hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Manifaxine hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Manifaxine hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.