Manifaxine
TL;DR: Manifaxine (CAS 135306-39-7) is a chemical compound with molecular formula C12H15F2NO2 and molecular weight 243.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethylmorpholin-2-ol
Also Known As: Manifaxine, manifaxina, manifaxinum, Manifaxine [INN:BAN], Manifaxine hydrochloride
| Molecular Formula | C12H15F2NO2 |
|---|---|
| Molecular Weight | 243.11 g/mol |
| LogP | 1.3 |
| Topological Polar Surface Area | 41.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 243.10709 |
| Heavy Atoms | 17 |
| Complexity | 269.0 |
Chemical Identifiers
| CAS Number | 135306-39-7 |
|---|---|
| SMILES | C[C@@H]1CO[C@]([C@@H](N1)C)(C2=CC(=CC(=C2)F)F)O |
| InChIKey | OZGPVYJHWWPEFT-RGNHYFCHSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Manifaxine (CAS 135306-39-7), with molecular formula C12H15F2NO2 and molecular weight 243.11 g/mol. IUPAC: (2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethylmorpholin-2-ol.
Chemical Property Profile of Manifaxine
Property Insights of Manifaxine
The XLogP value of 1.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Manifaxine. With a topological polar surface area (TPSA) of 41.5 Ų, Manifaxine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Manifaxine has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Manifaxine?
The CAS number of Manifaxine is 135306-39-7.
What is the molecular formula of Manifaxine?
The molecular formula of Manifaxine is C12H15F2NO2.
What is the molecular weight of Manifaxine?
The molecular weight of Manifaxine is 243.11 g/mol.
Where can I buy Manifaxine?
You can request a quote for Manifaxine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Manifaxine?
Yes, KEHONG BIO provides custom synthesis services for Manifaxine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.