Apadoline
TL;DR: Apadoline (CAS 135003-30-4) is a chemical compound with molecular formula C23H29N3OS and molecular weight 395.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-propyl-10-[(2R)-1-pyrrolidin-1-ylpropan-2-yl]phenothiazine-2-carboxamide
Also Known As: Apadoline, Apadoline [INN], Apadolina, SID:134221949, 3-(butylamino)-2-methyl-1,1-diphenylpropan-1-ol
| Molecular Formula | C23H29N3OS |
|---|---|
| Molecular Weight | 395.20 g/mol |
| LogP | 4.9 |
| Topological Polar Surface Area | 60.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 395.20312 |
| Heavy Atoms | 28 |
| Complexity | 524.0 |
Chemical Identifiers
| CAS Number | 135003-30-4 |
|---|---|
| SMILES | CCCNC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2[C@H](C)CN4CCCC4 |
| InChIKey | KXMAIWXPZGQNCR-QGZVFWFLSA-N |
Patent-Derived Application Labels
Derived from 3 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Apadoline (CAS 135003-30-4), with molecular formula C23H29N3OS and molecular weight 395.20 g/mol. IUPAC: N-propyl-10-[(2R)-1-pyrrolidin-1-ylpropan-2-yl]phenothiazine-2-carboxamide.
Chemical Property Profile of Apadoline
Property Insights of Apadoline
The XLogP value of 4.9 indicates that Apadoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Apadoline. Following Lipinski's Rule of Five, Apadoline has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Apadoline?
The CAS number of Apadoline is 135003-30-4.
What is the molecular formula of Apadoline?
The molecular formula of Apadoline is C23H29N3OS.
What is the molecular weight of Apadoline?
The molecular weight of Apadoline is 395.20 g/mol.
Where can I buy Apadoline?
You can request a quote for Apadoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Apadoline?
Yes, KEHONG BIO provides custom synthesis services for Apadoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.