2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine
TL;DR: 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine (CAS 134934-72-8) is a chemical compound with molecular formula C51H48N6O5 and molecular weight 824.37 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2R,3R,4R,5R)-2-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]-5-[6-[[(4-methoxyphenyl)-diphenylmethyl]amino]purin-9-yl]-4-(methylamino)oxolan-3-ol
Also Known As: 2'MeNH-5',N6(4MeOTrityl)dA, 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine, 9H-Purin-6-amine, 9-(2-deoxy-5-O-((4-methoxyphenyl)diphenylmethyl)-2-(methylamino)-beta-D-xylofuranosyl)-N-((4-methoxyphenyl)diphenylmethyl)-, (2R,3R,4R,5R)-2-[[(4-methoxyphenyl)-diphenyl-methoxy]methyl]-5-[6-[[(4-methoxyphenyl)-diphenyl-methyl]amino]purin-9-yl]-4-(methylamino)tetrahydrofuran-3-ol, (2R,3R,4R,5R)-2-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]-5-[6-[[(4-methoxyphenyl)-diphenylmethyl]amino]purin-9-yl]-4-(methylamino)oxolan-3-ol
| Molecular Formula | C51H48N6O5 |
|---|---|
| Molecular Weight | 824.37 g/mol |
| LogP | 8.3 |
| Topological Polar Surface Area | 125.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 15 |
| Exact Mass | 824.3686 |
| Heavy Atoms | 62 |
| Complexity | 1300.0 |
Chemical Identifiers
| CAS Number | 134934-72-8 |
|---|---|
| SMILES | CN[C@@H]1[C@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=C(C=C6)OC)COC(C7=CC=CC=C7)(C8=CC=CC=C8)C9=CC=C(C=C9)OC)O |
| InChIKey | KCXKCVIYYASMCS-PHXVDRCOSA-N |
Product Overview
2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine (CAS 134934-72-8), with molecular formula C51H48N6O5 and molecular weight 824.37 g/mol. IUPAC: (2R,3R,4R,5R)-2-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]-5-[6-[[(4-methoxyphenyl)-diphenylmethyl]amino]purin-9-yl]-4-(methylamino)oxolan-3-ol.
Chemical Property Profile of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine
Property Insights of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine
The XLogP value of 8.3 indicates that 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine. Following Lipinski's Rule of Five, 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine?
The CAS number of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine is 134934-72-8.
What is the molecular formula of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine?
The molecular formula of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine is C51H48N6O5.
What is the molecular weight of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine?
The molecular weight of 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine is 824.37 g/mol.
Where can I buy 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine?
You can request a quote for 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine?
Yes, KEHONG BIO provides custom synthesis services for 2'-Methylamino-5',N6-bis(4-methoxytrityl)-2'-deoxyadenosine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.