N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide
TL;DR: N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide (CAS 134880-96-9) is a chemical compound with molecular formula C6H4ClF3N2OS and molecular weight 243.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[5-chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl]acetamide
Also Known As: N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide, N-[5-chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl]acetamide
| Molecular Formula | C6H4ClF3N2OS |
|---|---|
| Molecular Weight | 243.97 g/mol |
| LogP | 2.3 |
| Topological Polar Surface Area | 70.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 243.96849 |
| Heavy Atoms | 14 |
| Complexity | 238.0 |
Chemical Identifiers
| CAS Number | 134880-96-9 |
|---|---|
| SMILES | CC(=O)NC1=NC(=C(S1)Cl)C(F)(F)F |
| InChIKey | AVVPZHSOMJYEIQ-UHFFFAOYSA-N |
Product Overview
N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide (CAS 134880-96-9), with molecular formula C6H4ClF3N2OS and molecular weight 243.97 g/mol. IUPAC: N-[5-chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl]acetamide.
Chemical Property Profile of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide
Property Insights of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide
The XLogP value of 2.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide. The TPSA of 70.2 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide. Following Lipinski's Rule of Five, N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide?
The CAS number of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide is 134880-96-9.
What is the molecular formula of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide?
The molecular formula of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide is C6H4ClF3N2OS.
What is the molecular weight of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide?
The molecular weight of N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide is 243.97 g/mol.
Where can I buy N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide?
You can request a quote for N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for N-(5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-yl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.