5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine
TL;DR: 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine (CAS 134880-91-4) is a chemical compound with molecular formula C4H2ClF3N2S and molecular weight 201.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine
Also Known As: 5-chloro-4-(trifluoromethyl)thiazol-2-amine, 5-chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine, 5-Chloro-4-(trifluoromethyl)-2-Thiazolamine, 5-Chloro-4-trifluoromethyl-thiazol-2-ylamine, 2-Amino-5-chloro-4-trifluoromethylthiazole
| Molecular Formula | C4H2ClF3N2S |
|---|---|
| Molecular Weight | 201.96 g/mol |
| LogP | 2.5 |
| Topological Polar Surface Area | 67.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 0 |
| Exact Mass | 201.95793 |
| Heavy Atoms | 11 |
| Complexity | 153.0 |
Chemical Identifiers
| CAS Number | 134880-91-4 |
|---|---|
| SMILES | C1(=C(SC(=N1)N)Cl)C(F)(F)F |
| InChIKey | WYSFDPSQZUDQKO-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine (CAS 134880-91-4), with molecular formula C4H2ClF3N2S and molecular weight 201.96 g/mol. IUPAC: 5-chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine.
Chemical Property Profile of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine
Property Insights of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine. The TPSA of 67.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine. Following Lipinski's Rule of Five, 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine?
The CAS number of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine is 134880-91-4.
What is the molecular formula of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine?
The molecular formula of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine is C4H2ClF3N2S.
What is the molecular weight of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine?
The molecular weight of 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine is 201.96 g/mol.
Where can I buy 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine?
You can request a quote for 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine?
Yes, KEHONG BIO provides custom synthesis services for 5-Chloro-4-(trifluoromethyl)-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.