Rosuvastatin
TL;DR: Rosuvastatin (CAS 1347797-73-2) is a chemical compound with molecular formula C22H30FN3O6S and molecular weight 483.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3R,5R)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyheptanoic acid
Also Known As: Rosuvastatin, Rosuvastatin EP Impurity L, 6,7-Dihydro Rosuvastatin Calcium Salt, (3R,5R)-7-[4-(4-fluorophenyl)-2-(N-methylmethanesulfonamido)-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyheptanoic acid, 7-[4-(4-FLUORO-PHENYL)-6-ISOPROPYL-2-(METHANESULFONYL-METHYL-AMINO)-PYRIMIDIN-5-YL] -3,5-DIHYDROXY-HEPTANOIC ACID
| Molecular Formula | C22H30FN3O6S |
|---|---|
| Molecular Weight | 483.18 g/mol |
| LogP | 2.3211 |
| Topological Polar Surface Area | 140.92 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 11 |
| Exact Mass | 483.18393 |
| Heavy Atoms | 33 |
| Complexity | 1076.2839 |
Chemical Identifiers
| CAS Number | 1347797-73-2 |
|---|---|
| SMILES | CC(C)C1=NC(=NC(=C1CC[C@H](C[C@H](CC(=O)O)O)O)C2=CC=C(C=C2)F)N(C)S(=O)(=O)C |
Product Overview
Rosuvastatin (CAS 1347797-73-2), with molecular formula C22H30FN3O6S and molecular weight 483.18 g/mol. IUPAC: (3R,5R)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyheptanoic acid.
Chemical Property Profile of Rosuvastatin
Property Insights of Rosuvastatin
The XLogP value of 2.3211 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Rosuvastatin. The TPSA of 140.92 Ų indicates high polarity, suggesting Rosuvastatin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Rosuvastatin has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Rosuvastatin?
The CAS number of Rosuvastatin is 1347797-73-2.
What is the molecular formula of Rosuvastatin?
The molecular formula of Rosuvastatin is C22H30FN3O6S.
What is the molecular weight of Rosuvastatin?
The molecular weight of Rosuvastatin is 483.18 g/mol.
Where can I buy Rosuvastatin?
You can request a quote for Rosuvastatin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Rosuvastatin?
Yes, KEHONG BIO provides custom synthesis services for Rosuvastatin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.