(Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one
TL;DR: (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one (CAS 1347744-85-7) is a chemical compound with molecular formula C14H15N3OS and molecular weight 273.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-2-piperidin-1-yl-5-(pyridin-4-ylmethylidene)-1,3-thiazol-4-one
Also Known As: J3.024.036G, (5Z)-2-Piperidino-5-[(4-pyridinyl)methylene]-2-thiazoline-4-one, (5Z)-2-piperidin-1-yl-5-(pyridin-4-ylmethylidene)-1,3-thiazol-4-one, (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one, 2-Piperidin-1-yl-5-[1-pyridin-4-yl-meth-(Z)-ylidene]-thiazol-4-one
| Molecular Formula | C14H15N3OS |
|---|---|
| Molecular Weight | 273.09 g/mol |
| LogP | 2.2 |
| Topological Polar Surface Area | 70.9 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 273.0936 |
| Heavy Atoms | 19 |
| Complexity | 407.0 |
Chemical Identifiers
| CAS Number | 1347744-85-7 |
|---|---|
| SMILES | C1CCN(CC1)C2=NC(=O)/C(=C/C3=CC=NC=C3)/S2 |
| InChIKey | GNAMRRQHNXPNPG-BENRWUELSA-N |
Product Overview
(Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one (CAS 1347744-85-7), with molecular formula C14H15N3OS and molecular weight 273.09 g/mol. IUPAC: (5Z)-2-piperidin-1-yl-5-(pyridin-4-ylmethylidene)-1,3-thiazol-4-one.
Chemical Property Profile of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one
Property Insights of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one. The TPSA of 70.9 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one. Following Lipinski's Rule of Five, (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one?
The CAS number of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one is 1347744-85-7.
What is the molecular formula of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one?
The molecular formula of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one is C14H15N3OS.
What is the molecular weight of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one?
The molecular weight of (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one is 273.09 g/mol.
Where can I buy (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one?
You can request a quote for (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-2-(piperidin-1-yl)-5-(pyridin-4-ylmethylene)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.