2',3'-Dideoxy-3'-thiacytidine
TL;DR: 2',3'-Dideoxy-3'-thiacytidine (CAS 134680-32-3) is a chemical compound with molecular formula C8H11N3O3S and molecular weight 229.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Also Known As: lamivudine, ent-Lamivudine, ent-?Lamivudine, Lamivudine, (+)-cis-, Lamivudine EP Impurity D
| Molecular Formula | C8H11N3O3S |
|---|---|
| Molecular Weight | 229.05 g/mol |
| LogP | -0.9 |
| Topological Polar Surface Area | 113.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 229.05211 |
| Heavy Atoms | 15 |
| Complexity | 331.0 |
Chemical Identifiers
| CAS Number | 134680-32-3 |
|---|---|
| SMILES | C1[C@@H](O[C@@H](S1)CO)N2C=CC(=NC2=O)N |
| InChIKey | JTEGQNOMFQHVDC-RQJHMYQMSA-N |
Patent-Derived Application Labels
Derived from 14 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2',3'-Dideoxy-3'-thiacytidine (CAS 134680-32-3), with molecular formula C8H11N3O3S and molecular weight 229.05 g/mol. IUPAC: 4-amino-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.
Chemical Property Profile of 2',3'-Dideoxy-3'-thiacytidine
Property Insights of 2',3'-Dideoxy-3'-thiacytidine
The XLogP value of -0.9 indicates that 2',3'-Dideoxy-3'-thiacytidine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 2',3'-Dideoxy-3'-thiacytidine. Following Lipinski's Rule of Five, 2',3'-Dideoxy-3'-thiacytidine has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2',3'-Dideoxy-3'-thiacytidine?
The CAS number of 2',3'-Dideoxy-3'-thiacytidine is 134680-32-3.
What is the molecular formula of 2',3'-Dideoxy-3'-thiacytidine?
The molecular formula of 2',3'-Dideoxy-3'-thiacytidine is C8H11N3O3S.
What is the molecular weight of 2',3'-Dideoxy-3'-thiacytidine?
The molecular weight of 2',3'-Dideoxy-3'-thiacytidine is 229.05 g/mol.
Where can I buy 2',3'-Dideoxy-3'-thiacytidine?
You can request a quote for 2',3'-Dideoxy-3'-thiacytidine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2',3'-Dideoxy-3'-thiacytidine?
Yes, KEHONG BIO provides custom synthesis services for 2',3'-Dideoxy-3'-thiacytidine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.