拉米夫定
TL;DR: 拉米夫定 (CAS 134678-17-4) is a chemical compound with molecular formula C8H11N3O3S and molecular weight 229.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
拉米夫定
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
Also Known As: lamivudine, Epivir, Zeffix, Heptovir, Epivir-HBV
| Molecular Formula | C8H11N3O3S |
|---|---|
| Molecular Weight | 229.05 g/mol |
| LogP | -0.9 |
| Topological Polar Surface Area | 113.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 229.05211 |
| Heavy Atoms | 15 |
| Complexity | 331.0 |
| Melting Point | 160-162 °C |
| Solubility | 70 |
| Vapor Pressure | 8.3X10-16 mm Hg @ 25 °C /Estimated/ |
Chemical Identifiers
| CAS Number | 134678-17-4 |
|---|---|
| SMILES | C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N |
| InChIKey | JTEGQNOMFQHVDC-NKWVEPMBSA-N |
Patent-Derived Application Labels
Derived from 9 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
拉米夫定 (CAS 134678-17-4), with molecular formula C8H11N3O3S and molecular weight 229.05 g/mol. IUPAC: 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one.
Chemical Property Profile of 拉米夫定
Property Insights of 拉米夫定
The XLogP value of -0.9 indicates that 拉米夫定 is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 113.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 拉米夫定. Following Lipinski's Rule of Five, 拉米夫定 has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 拉米夫定?
The CAS number of 拉米夫定 is 134678-17-4.
What is the molecular formula of 拉米夫定?
The molecular formula of 拉米夫定 is C8H11N3O3S.
What is the molecular weight of 拉米夫定?
The molecular weight of 拉米夫定 is 229.05 g/mol.
Where can I buy 拉米夫定?
You can request a quote for 拉米夫定 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 拉米夫定?
Yes, KEHONG BIO provides custom synthesis services for 拉米夫定 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.