Colchicine analog
TL;DR: Colchicine analog (CAS 134568-33-5) is a chemical compound with molecular formula C32H35NO9 and molecular weight 577.23 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
Also Known As: Colchicine analog, N-(3,4,5-Trimethoxycinnamoyl)-N-deacetylcolchicine, Benzo[a]heptalene, 2-propenamide deriv., 2-Propenamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)-3-(3,4,5-trimethoxyphenyl)-, (S)-, (E)-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide
| Molecular Formula | C32H35NO9 |
|---|---|
| Molecular Weight | 577.23 g/mol |
| LogP | 4.5909 |
| Topological Polar Surface Area | 110.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 577.2312 |
| Heavy Atoms | 42 |
| Complexity | 1539.7847 |
Chemical Identifiers
| CAS Number | 134568-33-5 |
|---|---|
| SMILES | COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)/C=C/C4=CC(=C(C(=C4)OC)OC)OC |
Product Overview
Colchicine analog (CAS 134568-33-5), with molecular formula C32H35NO9 and molecular weight 577.23 g/mol. IUPAC: (E)-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide.
Chemical Property Profile of Colchicine analog
Property Insights of Colchicine analog
The XLogP value of 4.5909 indicates that Colchicine analog is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 110.78 Ų falls within the moderate polarity range, balancing permeability and solubility for Colchicine analog. Following Lipinski's Rule of Five, Colchicine analog has 1 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Colchicine analog?
The CAS number of Colchicine analog is 134568-33-5.
What is the molecular formula of Colchicine analog?
The molecular formula of Colchicine analog is C32H35NO9.
What is the molecular weight of Colchicine analog?
The molecular weight of Colchicine analog is 577.23 g/mol.
Where can I buy Colchicine analog?
You can request a quote for Colchicine analog directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Colchicine analog?
Yes, KEHONG BIO provides custom synthesis services for Colchicine analog and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.