N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine
TL;DR: N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine (CAS 134568-32-4) is a chemical compound with molecular formula C39H41NO12 and molecular weight 715.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3,4,5-trimethoxy-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(3,4,5-trimethoxybenzoyl)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide
Also Known As: Colchicine analog, N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine, 3,4,5-trimethoxy-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(3,4,5-trimethoxybenzoyl)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide, Benzamide, 3,4,5-trimethoxy-N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxo-10-(3,4,5-trimethoxybenzoyl)benzo(a)heptalen-7-yl)-, (S)-, 3,4,5-Trimethoxy-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(3,4,5-trimethoxybenzoyl)-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]benzamide
| Molecular Formula | C39H41NO12 |
|---|---|
| Molecular Weight | 715.26 g/mol |
| LogP | 4.4 |
| Topological Polar Surface Area | 146.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 12 |
| Rotatable Bonds | 13 |
| Exact Mass | 715.2629 |
| Heavy Atoms | 52 |
| Complexity | 1330.0 |
Chemical Identifiers
| CAS Number | 134568-32-4 |
|---|---|
| SMILES | COC1=CC(=CC(=C1OC)OC)C(=O)C2=CC=C3C(=CC2=O)[C@H](CCC4=CC(=C(C(=C43)OC)OC)OC)NC(=O)C5=CC(=C(C(=C5)OC)OC)OC |
| InChIKey | GLBVIONDQFXZJW-SANMLTNESA-N |
Product Overview
N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine (CAS 134568-32-4), with molecular formula C39H41NO12 and molecular weight 715.26 g/mol. IUPAC: 3,4,5-trimethoxy-N-[(7S)-1,2,3-trimethoxy-9-oxo-10-(3,4,5-trimethoxybenzoyl)-6,7-dihydro-5H-benzo[a]heptalen-7-yl]benzamide.
Chemical Property Profile of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine
Property Insights of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine
The XLogP value of 4.4 indicates that N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 146.0 Ų indicates high polarity, suggesting N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine has 1 hydrogen bond donor(s) and 12 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine?
The CAS number of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine is 134568-32-4.
What is the molecular formula of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine?
The molecular formula of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine is C39H41NO12.
What is the molecular weight of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine?
The molecular weight of N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine is 715.26 g/mol.
Where can I buy N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine?
You can request a quote for N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine?
Yes, KEHONG BIO provides custom synthesis services for N,10-bis-(3,4,5-Trimethoxybenzoyl)-N-deacetyl-10-demethylcolchicine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.