1,2,3-Demethylcolchiceine
TL;DR: 1,2,3-Demethylcolchiceine (CAS 134568-30-2) is a chemical compound with molecular formula C18H17NO6 and molecular weight 343.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(7S)-1,2,3,10-tetrahydroxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Also Known As: 1,2,3-Demethylcolchiceine, Colchiceine analog, N-[(7S)-1,2,3,10-tetrahydroxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide, Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetrahydroxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-, Acetamide, N-(5,6,7,9-tetrahydro-1,2,3,10-tetrahydroxy-9-oxobenzo(a)heptalen-7-yl)-, (S)-
| Molecular Formula | C18H17NO6 |
|---|---|
| Molecular Weight | 343.11 g/mol |
| LogP | 0.2 |
| Topological Polar Surface Area | 127.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 343.1056 |
| Heavy Atoms | 25 |
| Complexity | 679.0 |
Chemical Identifiers
| CAS Number | 134568-30-2 |
|---|---|
| SMILES | CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)O)O)O |
| InChIKey | AQAJIZGCFLTZFB-LBPRGKRZSA-N |
Product Overview
1,2,3-Demethylcolchiceine (CAS 134568-30-2), with molecular formula C18H17NO6 and molecular weight 343.11 g/mol. IUPAC: N-[(7S)-1,2,3,10-tetrahydroxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide.
Chemical Property Profile of 1,2,3-Demethylcolchiceine
Property Insights of 1,2,3-Demethylcolchiceine
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1,2,3-Demethylcolchiceine. The TPSA of 127.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 1,2,3-Demethylcolchiceine. Following Lipinski's Rule of Five, 1,2,3-Demethylcolchiceine has 5 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1,2,3-Demethylcolchiceine?
The CAS number of 1,2,3-Demethylcolchiceine is 134568-30-2.
What is the molecular formula of 1,2,3-Demethylcolchiceine?
The molecular formula of 1,2,3-Demethylcolchiceine is C18H17NO6.
What is the molecular weight of 1,2,3-Demethylcolchiceine?
The molecular weight of 1,2,3-Demethylcolchiceine is 343.11 g/mol.
Where can I buy 1,2,3-Demethylcolchiceine?
You can request a quote for 1,2,3-Demethylcolchiceine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1,2,3-Demethylcolchiceine?
Yes, KEHONG BIO provides custom synthesis services for 1,2,3-Demethylcolchiceine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.