UK 21
TL;DR: UK 21 (CAS 134423-92-0) is a chemical compound with molecular formula C39H62FN5O12 and molecular weight 811.44 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(2R,3R,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-bis[[2-(2-propylpentanoylamino)acetyl]oxy]oxolan-2-yl]methyl 2-(2-propylpentanoylamino)acetate
Also Known As: UK 21, 2',3',5'-Tris-O-(N -(2-n-propyl-n-pentanoyl)glycyl)-5-fluorouridine, [(2R,3R,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-bis[[2-(2-propylpentanoylamino)acetyl]oxy]oxolan-2-yl]methyl 2-(2-propylpentanoylamino)acetate, 2',3',5'-Tris-O-(N-(2-n-propyl-n-pentanoyl)glycyl)-5-fluorouridine, Glycine, N-(1-oxo-2-propylpentyl)-, triester with 5-fluorouridine
| Molecular Formula | C39H62FN5O12 |
|---|---|
| Molecular Weight | 811.44 g/mol |
| LogP | 5.7 |
| Topological Polar Surface Area | 225.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 13 |
| Rotatable Bonds | 29 |
| Exact Mass | 811.4379 |
| Heavy Atoms | 57 |
| Complexity | 1410.0 |
Chemical Identifiers
| CAS Number | 134423-92-0 |
|---|---|
| SMILES | CCCC(CCC)C(=O)NCC(=O)OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)OC(=O)CNC(=O)C(CCC)CCC)OC(=O)CNC(=O)C(CCC)CCC |
| InChIKey | BRWICCRLZVPGRD-DKMDIHIKSA-N |
Patent-Derived Application Labels
Derived from 2 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
UK 21 (CAS 134423-92-0), with molecular formula C39H62FN5O12 and molecular weight 811.44 g/mol. IUPAC: [(2R,3R,4R,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3,4-bis[[2-(2-propylpentanoylamino)acetyl]oxy]oxolan-2-yl]methyl 2-(2-propylpentanoylamino)acetate.
Chemical Property Profile of UK 21
Property Insights of UK 21
The XLogP value of 5.7 indicates that UK 21 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 225.0 Ų indicates high polarity, suggesting UK 21 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, UK 21 has 4 hydrogen bond donor(s) and 13 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of UK 21?
The CAS number of UK 21 is 134423-92-0.
What is the molecular formula of UK 21?
The molecular formula of UK 21 is C39H62FN5O12.
What is the molecular weight of UK 21?
The molecular weight of UK 21 is 811.44 g/mol.
Where can I buy UK 21?
You can request a quote for UK 21 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for UK 21?
Yes, KEHONG BIO provides custom synthesis services for UK 21 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.