NCI 144-147
TL;DR: NCI 144-147 (CAS 13440-40-9) is a chemical compound with molecular formula C40H53NO14 and molecular weight 771.35 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[(9E,19E,21Z)-26-(dimethoxymethyl)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl] acetate
Also Known As: NCI 144-147, [(9E,19E,21Z)-26-(dimethoxymethyl)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl] acetate, 2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-8-carboxaldehyde, 1,2-dihydro-5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-, 8-(dimethylacetal), 21-acetate
| Molecular Formula | C40H53NO14 |
|---|---|
| Molecular Weight | 771.35 g/mol |
| LogP | 5.04552 |
| Topological Polar Surface Area | 219.77 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 5 |
| Exact Mass | 771.3466 |
| Heavy Atoms | 55 |
| Complexity | 1898.1338 |
Chemical Identifiers
| CAS Number | 13440-40-9 |
|---|---|
| SMILES | CC1/C=C/C=C(\C(=O)NC2=C(C3=C(C4=C(C(=C3O)C)OC(C4=O)(O/C=C/C(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C(=C2C(OC)OC)O)O)/C |
Product Overview
NCI 144-147 (CAS 13440-40-9), with molecular formula C40H53NO14 and molecular weight 771.35 g/mol. IUPAC: [(9E,19E,21Z)-26-(dimethoxymethyl)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl] acetate.
Chemical Property Profile of NCI 144-147
Property Insights of NCI 144-147
The XLogP value of 5.04552 indicates that NCI 144-147 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 219.77 Ų indicates high polarity, suggesting NCI 144-147 may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, NCI 144-147 has 6 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of NCI 144-147?
The CAS number of NCI 144-147 is 13440-40-9.
What is the molecular formula of NCI 144-147?
The molecular formula of NCI 144-147 is C40H53NO14.
What is the molecular weight of NCI 144-147?
The molecular weight of NCI 144-147 is 771.35 g/mol.
Where can I buy NCI 144-147?
You can request a quote for NCI 144-147 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for NCI 144-147?
Yes, KEHONG BIO provides custom synthesis services for NCI 144-147 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.