3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate
TL;DR: 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate (CAS 134309-68-5) is a chemical compound with molecular formula C15H25N6O6P and molecular weight 416.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S,5S)-4-azido-5-[[ethoxy(propylamino)phosphoryl]oxymethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: PrNHPO3(Et)AZT, 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate, Thymidine, 3'-azido-3'-deoxy-, 5'-(ethyl propylphosphoramidate), 1-[(2R,4S,5S)-4-azido-5-[[ethoxy(propylamino)phosphoryl]oxymethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione, 1-[(2R,4S,5S)-4-azido-5-[[ethoxy(propylamino)phosphoryl]oxymethyl]tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione
| Molecular Formula | C15H25N6O6P |
|---|---|
| Molecular Weight | 416.16 g/mol |
| LogP | 1.0 |
| Topological Polar Surface Area | 121.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 10 |
| Exact Mass | 416.15732 |
| Heavy Atoms | 28 |
| Complexity | 724.0 |
Chemical Identifiers
| CAS Number | 134309-68-5 |
|---|---|
| SMILES | CCCNP(=O)(OCC)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)C)N=[N+]=[N-] |
| InChIKey | PDEDLARIGSZJLG-QDSMQDDISA-N |
Product Overview
3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate (CAS 134309-68-5), with molecular formula C15H25N6O6P and molecular weight 416.16 g/mol. IUPAC: 1-[(2R,4S,5S)-4-azido-5-[[ethoxy(propylamino)phosphoryl]oxymethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione.
Chemical Property Profile of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate
Property Insights of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate
The XLogP value of 1.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate. The TPSA of 121.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate. Following Lipinski's Rule of Five, 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate has 2 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate?
The CAS number of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate is 134309-68-5.
What is the molecular formula of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate?
The molecular formula of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate is C15H25N6O6P.
What is the molecular weight of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate?
The molecular weight of 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate is 416.16 g/mol.
Where can I buy 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate?
You can request a quote for 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate?
Yes, KEHONG BIO provides custom synthesis services for 3'-Azido-3'-deoxythymidine-5'-(ethyl propylamino)phosphoramidate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.