![5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one structure](/static/products/134/134277-23-9.png)
5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one
TL;DR: 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one (CAS 134277-23-9) is a chemical compound with molecular formula C16H12FN3O and molecular weight 281.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-fluorophenyl)spiro[1,4-dihydropyrazole-5,3'-1H-indole]-2'-one
Also Known As: 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one, 3-(4-fluorophenyl)spiro[1,4-dihydropyrazole-5,3'-1H-indole]-2'-one, 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indoline-3,3'-pyrazol]-2-one, 5'-(4-fluorophenyl)spiro[1H-indole-3,3'-2,4-dihydropyrazole]-2-one
| Molecular Formula | C16H12FN3O |
|---|---|
| Molecular Weight | 281.10 g/mol |
| LogP | 2.3707 |
| Topological Polar Surface Area | 53.49 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 281.09644 |
| Heavy Atoms | 21 |
| Complexity | 769.3465 |
Chemical Identifiers
| CAS Number | 134277-23-9 |
|---|---|
| SMILES | C1C(=NNC12C3=CC=CC=C3NC2=O)C4=CC=C(C=C4)F |
Product Overview
5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one (CAS 134277-23-9), with molecular formula C16H12FN3O and molecular weight 281.10 g/mol. IUPAC: 3-(4-fluorophenyl)spiro[1,4-dihydropyrazole-5,3'-1H-indole]-2'-one.
Chemical Property Profile of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one
Property Insights of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one
The XLogP value of 2.3707 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one. With a topological polar surface area (TPSA) of 53.49 Ų, 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one?
The CAS number of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one is 134277-23-9.
What is the molecular formula of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one?
The molecular formula of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one is C16H12FN3O.
What is the molecular weight of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one?
The molecular weight of 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one is 281.10 g/mol.
Where can I buy 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one?
You can request a quote for 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5'-(4-fluorophenyl)-2',4'-dihydrospiro[indole-3,3'-pyrazol]-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.