MeOCOPrNHPO3(Et)AZT
TL;DR: MeOCOPrNHPO3(Et)AZT (CAS 134250-46-7) is a chemical compound with molecular formula C17H27N6O8P and molecular weight 474.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
methyl 4-[[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-ethoxyphosphoryl]amino]butanoate
Also Known As: MeOCOPrNHPO3(Et)AZT, 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-4-aminobutyl)phosphoramidate, methyl 4-[[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-ethoxy-phosphoryl]amino]butanoate, Thymidine, 3'-azido-3'-deoxy-, 5'-[ethyl (4-methoxy-4-oxobutyl)phosphoramidate], -, 1-(3-Azido-2,3-dideoxy-5-O-{ethoxy[(4-methoxy-4-oxobutyl)amino]phosphoryl}-beta-D-erythro-pentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
| Molecular Formula | C17H27N6O8P |
|---|---|
| Molecular Weight | 474.16 g/mol |
| LogP | 0.3 |
| Topological Polar Surface Area | 147.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 13 |
| Exact Mass | 474.1628 |
| Heavy Atoms | 32 |
| Complexity | 845.0 |
Chemical Identifiers
| CAS Number | 134250-46-7 |
|---|---|
| SMILES | CCOP(=O)(NCCCC(=O)OC)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)C)N=[N+]=[N-] |
| InChIKey | WJZMAVPYIKSQFR-CONJGFJISA-N |
Product Overview
MeOCOPrNHPO3(Et)AZT (CAS 134250-46-7), with molecular formula C17H27N6O8P and molecular weight 474.16 g/mol. IUPAC: methyl 4-[[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-ethoxyphosphoryl]amino]butanoate.
Chemical Property Profile of MeOCOPrNHPO3(Et)AZT
Property Insights of MeOCOPrNHPO3(Et)AZT
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for MeOCOPrNHPO3(Et)AZT. The TPSA of 147.0 Ų indicates high polarity, suggesting MeOCOPrNHPO3(Et)AZT may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, MeOCOPrNHPO3(Et)AZT has 2 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of MeOCOPrNHPO3(Et)AZT?
The CAS number of MeOCOPrNHPO3(Et)AZT is 134250-46-7.
What is the molecular formula of MeOCOPrNHPO3(Et)AZT?
The molecular formula of MeOCOPrNHPO3(Et)AZT is C17H27N6O8P.
What is the molecular weight of MeOCOPrNHPO3(Et)AZT?
The molecular weight of MeOCOPrNHPO3(Et)AZT is 474.16 g/mol.
Where can I buy MeOCOPrNHPO3(Et)AZT?
You can request a quote for MeOCOPrNHPO3(Et)AZT directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for MeOCOPrNHPO3(Et)AZT?
Yes, KEHONG BIO provides custom synthesis services for MeOCOPrNHPO3(Et)AZT and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.