L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride structure

L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride

TL;DR: L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride (CAS 134185-45-8) is a chemical compound with molecular formula C20H28ClN5O5 and molecular weight 453.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[(3S,3aR,6S,6aS)-3-[4-(3-indazol-2-ylpropyl)piperazin-1-yl]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate;hydrochloride

Also Known As: L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride, [(3S,3aR,6S,6aS)-3-[4-(3-indazol-2-ylpropyl)piperazin-1-yl]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate hydrochloride, 1,4:3,6-Dianhydro-2-deoxy-2-{4-[3-(2H-indazol-2-yl)propyl]piperazin-1-yl}-5-O-nitro-L-iditol--hydrogen chloride (1/1), 1,4:3,6-Dianhydro-2-deoxy-2-{4-[3-(2H-indazol-2-yl)propyl]piperazin-1-yl}-5-O-nitrohexitol--hydrogen chloride (1/1), RefChem:350731

CAS: 134185-45-8
Molecular Formula C20H28ClN5O5
Molecular Weight 453.18 g/mol
LogP 1.2089
Topological Polar Surface Area 95.13 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 8
Rotatable Bonds 7
Exact Mass 453.1779
Heavy Atoms 31
Complexity 856.72266

Chemical Identifiers

CAS Number 134185-45-8
SMILES C1CN(CCN1CCCN2C=C3C=CC=CC3=N2)[C@H]4CO[C@H]5[C@@H]4OC[C@@H]5O[N+](=O)[O-].Cl

Product Overview

L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride (CAS 134185-45-8), with molecular formula C20H28ClN5O5 and molecular weight 453.18 g/mol. IUPAC: [(3S,3aR,6S,6aS)-3-[4-(3-indazol-2-ylpropyl)piperazin-1-yl]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate;hydrochloride.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride

XLogP
1.2089
TPSA (Topological Polar Surface Area)
95.13
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
8
Rotatable Bonds
7
Heavy Atoms
31
Complexity
856.72266
Exact Mass
453.1779
Monoisotopic Mass
453.1779
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride

The XLogP value of 1.2089 suggests moderate lipophilicity, balancing water solubility and membrane permeability for L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride. The TPSA of 95.13 Ų falls within the moderate polarity range, balancing permeability and solubility for L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride. Following Lipinski's Rule of Five, L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride?

The CAS number of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride is 134185-45-8.

What is the molecular formula of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride?

The molecular formula of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride is C20H28ClN5O5.

What is the molecular weight of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride?

The molecular weight of L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride is 453.18 g/mol.

Where can I buy L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride?

You can request a quote for L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride?

Yes, KEHONG BIO provides custom synthesis services for L-Iditol, 1,4:3,6-dianhydro-2-deoxy-2-(4-(3-(2H-indazol-2-yl)propyl)-1-piperazinyl)-, 5-nitrate, hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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