TDN345
TL;DR: TDN345 (CAS 134069-68-4) is a chemical compound with molecular formula C28H34F2N2O2 and molecular weight 468.26 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
8-[4,4-bis(4-fluorophenyl)butyl]-3-tert-butyl-4-methylidene-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Also Known As: TDN345, TDN 345, 8-[4,4-bis(4-fluorophenyl)butyl]-3-tert-butyl-4-methylidene-1-oxa-3,8-diazaspiro[4.5]decan-2-one, 1-Oxa-3,8-diazaspiro(4.5)decan-2-one, 8-(4,4-bis(4-fluorophenyl)butyl)-3-(1,1-dimethylethyl)-4-methylene-, 8-(4,4-Bis(4-fluorophenyl)butyl)-3-(tert-butyl)-4-methylene-1-oxa-3,8-diazaspiro[4.5]decan-2-one
| Molecular Formula | C28H34F2N2O2 |
|---|---|
| Molecular Weight | 468.26 g/mol |
| LogP | 6.4759 |
| Topological Polar Surface Area | 32.78 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 468.25882 |
| Heavy Atoms | 34 |
| Complexity | 974.3668 |
Chemical Identifiers
| CAS Number | 134069-68-4 |
|---|---|
| SMILES | CC(C)(C)N1C(=C)C2(CCN(CC2)CCCC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F)OC1=O |
Product Overview
TDN345 (CAS 134069-68-4), with molecular formula C28H34F2N2O2 and molecular weight 468.26 g/mol. IUPAC: 8-[4,4-bis(4-fluorophenyl)butyl]-3-tert-butyl-4-methylidene-1-oxa-3,8-diazaspiro[4.5]decan-2-one.
Chemical Property Profile of TDN345
Property Insights of TDN345
The XLogP value of 6.4759 indicates that TDN345 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.78 Ų, TDN345 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, TDN345 has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of TDN345?
The CAS number of TDN345 is 134069-68-4.
What is the molecular formula of TDN345?
The molecular formula of TDN345 is C28H34F2N2O2.
What is the molecular weight of TDN345?
The molecular weight of TDN345 is 468.26 g/mol.
Where can I buy TDN345?
You can request a quote for TDN345 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for TDN345?
Yes, KEHONG BIO provides custom synthesis services for TDN345 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.