18-Hydroxycamptothecin
TL;DR: 18-Hydroxycamptothecin (CAS 13404-92-7) is a chemical compound with molecular formula C20H16N2O5 and molecular weight 364.11 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(19S)-19-hydroxy-19-(2-hydroxyethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Also Known As: 18-Hydroxycamptothecin, Tetrasulfide,didecyl, 20-hydroxycamptothecin, 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-hydroxy-4-(2-hydroxyethyl)-, (S)-, 1h-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione, 4-hydroxy-4-(2-hydroxyethyl)-,(s)-
| Molecular Formula | C20H16N2O5 |
|---|---|
| Molecular Weight | 364.11 g/mol |
| LogP | 0.3 |
| Topological Polar Surface Area | 100.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 364.10593 |
| Heavy Atoms | 27 |
| Complexity | 759.0 |
Chemical Identifiers
| CAS Number | 13404-92-7 |
|---|---|
| SMILES | C1C2=CC3=CC=CC=C3N=C2C4=CC5=C(COC(=O)[C@@]5(CCO)O)C(=O)N41 |
| InChIKey | CCBXXGSAGQNXHX-FQEVSTJZSA-N |
Product Overview
18-Hydroxycamptothecin (CAS 13404-92-7), with molecular formula C20H16N2O5 and molecular weight 364.11 g/mol. IUPAC: (19S)-19-hydroxy-19-(2-hydroxyethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione.
Chemical Property Profile of 18-Hydroxycamptothecin
Property Insights of 18-Hydroxycamptothecin
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 18-Hydroxycamptothecin. The TPSA of 100.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 18-Hydroxycamptothecin. Following Lipinski's Rule of Five, 18-Hydroxycamptothecin has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 18-Hydroxycamptothecin?
The CAS number of 18-Hydroxycamptothecin is 13404-92-7.
What is the molecular formula of 18-Hydroxycamptothecin?
The molecular formula of 18-Hydroxycamptothecin is C20H16N2O5.
What is the molecular weight of 18-Hydroxycamptothecin?
The molecular weight of 18-Hydroxycamptothecin is 364.11 g/mol.
Where can I buy 18-Hydroxycamptothecin?
You can request a quote for 18-Hydroxycamptothecin directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 18-Hydroxycamptothecin?
Yes, KEHONG BIO provides custom synthesis services for 18-Hydroxycamptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.