2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide
TL;DR: 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide (CAS 133790-13-3) is a chemical compound with molecular formula C23H27N5O5 and molecular weight 453.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-[[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]amino]-N-(2-amino-2-oxoethyl)-3-(4-hydroxyphenyl)propanamide
Also Known As: IS159, IS 159, 2-(3-(2-aminoethyl)-1h-indol-5-yloxy)acetyl-l-tyrosyl-glycinamide, (2S)-2-[[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]amino]-N-(2-amino-2-oxoethyl)-3-(4-hydroxyphenyl)propanamide, [[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-L-Tyr-Gly-NH2
| Molecular Formula | C23H27N5O5 |
|---|---|
| Molecular Weight | 453.20 g/mol |
| LogP | 0.6 |
| Topological Polar Surface Area | 173.0 Ų |
| Hydrogen Bond Donors | 6 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 11 |
| Exact Mass | 453.20123 |
| Heavy Atoms | 33 |
| Complexity | 670.0 |
Chemical Identifiers
| CAS Number | 133790-13-3 |
|---|---|
| SMILES | C1=CC(=CC=C1C[C@@H](C(=O)NCC(=O)N)NC(=O)COC2=CC3=C(C=C2)NC=C3CCN)O |
| InChIKey | PBRWGFLPYQYNGI-FQEVSTJZSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide (CAS 133790-13-3), with molecular formula C23H27N5O5 and molecular weight 453.20 g/mol. IUPAC: (2S)-2-[[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]amino]-N-(2-amino-2-oxoethyl)-3-(4-hydroxyphenyl)propanamide.
Chemical Property Profile of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide
Property Insights of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide. The TPSA of 173.0 Ų indicates high polarity, suggesting 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide has 6 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide?
The CAS number of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide is 133790-13-3.
What is the molecular formula of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide?
The molecular formula of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide is C23H27N5O5.
What is the molecular weight of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide?
The molecular weight of 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide is 453.20 g/mol.
Where can I buy 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide?
You can request a quote for 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide?
Yes, KEHONG BIO provides custom synthesis services for 2-(3-(2-Aminoethyl)-1H-indol-5-yloxy)acetyl-L-tyrosyl-glycinamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.