4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline
TL;DR: 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline (CAS 133671-70-2) is a chemical compound with molecular formula C18H19N3S and molecular weight 309.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(4-methylpiperazin-1-yl)-2-thiophen-2-ylquinoline
Also Known As: Quinoline deriv., 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline, 4-(4-Methylpiperazino)-2-(2-thienyl)quinoline, 4-(4-Methylpiperazin-1-yl)-2-(thiophen-2-yl)quinoline, 4-(4-methylpiperazin-1-yl)-2-thiophen-2-ylquinoline
| Molecular Formula | C18H19N3S |
|---|---|
| Molecular Weight | 309.13 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 47.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 309.12997 |
| Heavy Atoms | 22 |
| Complexity | 369.0 |
Chemical Identifiers
| CAS Number | 133671-70-2 |
|---|---|
| SMILES | CN1CCN(CC1)C2=CC(=NC3=CC=CC=C32)C4=CC=CS4 |
| InChIKey | OHIXLXNUKMHJJF-UHFFFAOYSA-N |
Product Overview
4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline (CAS 133671-70-2), with molecular formula C18H19N3S and molecular weight 309.13 g/mol. IUPAC: 4-(4-methylpiperazin-1-yl)-2-thiophen-2-ylquinoline.
Chemical Property Profile of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline
Property Insights of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline
The XLogP value of 3.5 indicates that 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.6 Ų, 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline?
The CAS number of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline is 133671-70-2.
What is the molecular formula of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline?
The molecular formula of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline is C18H19N3S.
What is the molecular weight of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline?
The molecular weight of 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline is 309.13 g/mol.
Where can I buy 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline?
You can request a quote for 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline?
Yes, KEHONG BIO provides custom synthesis services for 4-(4-Methyl-1-piperazinyl)-2-(2-thienyl)quinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.