Tyrphostin B44
TL;DR: Tyrphostin B44 (CAS 133550-32-0) is a chemical compound with molecular formula C18H16N2O3 and molecular weight 308.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]prop-2-enamide
Also Known As: Tyrphostin B44, Tyrphostin AG 527, Tyrphostin B44, (-) enantiomer, Tyrphostin B-44, Tyrphostin B44(-)
| Molecular Formula | C18H16N2O3 |
|---|---|
| Molecular Weight | 308.12 g/mol |
| LogP | 2.88218 |
| Topological Polar Surface Area | 93.35 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 308.1161 |
| Heavy Atoms | 23 |
| Complexity | 776.5989 |
Chemical Identifiers
| CAS Number | 133550-32-0 |
|---|---|
| SMILES | C[C@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N |
Product Overview
Tyrphostin B44 (CAS 133550-32-0), with molecular formula C18H16N2O3 and molecular weight 308.12 g/mol. IUPAC: (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]prop-2-enamide.
Chemical Property Profile of Tyrphostin B44
Property Insights of Tyrphostin B44
The XLogP value of 2.88218 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tyrphostin B44. The TPSA of 93.35 Ų falls within the moderate polarity range, balancing permeability and solubility for Tyrphostin B44. Following Lipinski's Rule of Five, Tyrphostin B44 has 3 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tyrphostin B44?
The CAS number of Tyrphostin B44 is 133550-32-0.
What is the molecular formula of Tyrphostin B44?
The molecular formula of Tyrphostin B44 is C18H16N2O3.
What is the molecular weight of Tyrphostin B44?
The molecular weight of Tyrphostin B44 is 308.12 g/mol.
Where can I buy Tyrphostin B44?
You can request a quote for Tyrphostin B44 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tyrphostin B44?
Yes, KEHONG BIO provides custom synthesis services for Tyrphostin B44 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.