1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil
TL;DR: 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil (CAS 133488-41-2) is a chemical compound with molecular formula C10H14ClN3O5 and molecular weight 291.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
1-[(2R,4S)-4-amino-5-[(1S)-1,2-dihydroxyethyl]oxolan-2-yl]-5-chloropyrimidine-2,4-dione
Also Known As: 3NH-D-ribo-ddT deriv., 3NH-D-ribo-ddU deriv., 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil, 2,4(1H,3H)-Pyrimidinedione, 1-(3-amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chloro-, 1-[(2R,4S)-4-amino-5-[(1S)-1,2-dihydroxyethyl]oxolan-2-yl]-5-chloropyrimidine-2,4-dione
| Molecular Formula | C10H14ClN3O5 |
|---|---|
| Molecular Weight | 291.06 g/mol |
| LogP | -1.6 |
| Topological Polar Surface Area | 125.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 291.0622 |
| Heavy Atoms | 19 |
| Complexity | 429.0 |
Chemical Identifiers
| CAS Number | 133488-41-2 |
|---|---|
| SMILES | C1[C@@H](C(O[C@H]1N2C=C(C(=O)NC2=O)Cl)[C@H](CO)O)N |
| InChIKey | OARFQCHQOAHGCU-QBARFFCXSA-N |
Product Overview
1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil (CAS 133488-41-2), with molecular formula C10H14ClN3O5 and molecular weight 291.06 g/mol. IUPAC: 1-[(2R,4S)-4-amino-5-[(1S)-1,2-dihydroxyethyl]oxolan-2-yl]-5-chloropyrimidine-2,4-dione.
Chemical Property Profile of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil
Property Insights of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil
The XLogP value of -1.6 indicates that 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil. Following Lipinski's Rule of Five, 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil has 4 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil?
The CAS number of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil is 133488-41-2.
What is the molecular formula of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil?
The molecular formula of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil is C10H14ClN3O5.
What is the molecular weight of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil?
The molecular weight of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil is 291.06 g/mol.
Where can I buy 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil?
You can request a quote for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil?
Yes, KEHONG BIO provides custom synthesis services for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-chlorouracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.