Losoxantrone hydrochloride
TL;DR: Losoxantrone hydrochloride (CAS 132937-89-4) is a chemical compound with molecular formula C44H60Cl4N10O9 and molecular weight 1012.33 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
bis(6-hydroxy-14-[2-(2-hydroxyethylamino)ethyl]-10-[2-(2-hydroxyethylamino)ethylamino]-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one);hydrate;tetrahydrochloride
Also Known As: Losoxantrone HCl, Losoxantrone hydrochloride, Losoxantrone hydrochloride [USAN], losoxantrone hydrochloride hydrate, DUP 941
| Molecular Formula | C44H60Cl4N10O9 |
|---|---|
| Molecular Weight | 1012.33 g/mol |
| LogP | 1.9205 |
| Topological Polar Surface Area | 264.0 Ų |
| Hydrogen Bond Donors | 17 |
| Hydrogen Bond Acceptors | 17 |
| Rotatable Bonds | 22 |
| Exact Mass | 1012.3299 |
| Heavy Atoms | 67 |
| Complexity | 596.0 |
Chemical Identifiers
| CAS Number | 132937-89-4 |
|---|---|
| SMILES | C1=CC2=C(C(=C1)O)C(=O)C3=C(C=CC4=C3C2=NN4CCNCCO)NCCNCCO.C1=CC2=C(C(=C1)O)C(=O)C3=C(C=CC4=C3C2=NN4CCNCCO)NCCNCCO.O.Cl.Cl.Cl.Cl |
| InChIKey | CNQCTSLNJJVSAU-UHFFFAOYSA-N |
Product Overview
Losoxantrone hydrochloride (CAS 132937-89-4), with molecular formula C44H60Cl4N10O9 and molecular weight 1012.33 g/mol. IUPAC: bis(6-hydroxy-14-[2-(2-hydroxyethylamino)ethyl]-10-[2-(2-hydroxyethylamino)ethylamino]-14,15-diazatetracyclo[7.6.1.02,7.013,16]hexadeca-1(15),2(7),3,5,9,11,13(16)-heptaen-8-one);hydrate;tetrahydrochloride.
Chemical Property Profile of Losoxantrone hydrochloride
Property Insights of Losoxantrone hydrochloride
The XLogP value of 1.9205 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Losoxantrone hydrochloride. The TPSA of 264.0 Ų indicates high polarity, suggesting Losoxantrone hydrochloride may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Losoxantrone hydrochloride has 17 hydrogen bond donor(s) and 17 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Losoxantrone hydrochloride?
The CAS number of Losoxantrone hydrochloride is 132937-89-4.
What is the molecular formula of Losoxantrone hydrochloride?
The molecular formula of Losoxantrone hydrochloride is C44H60Cl4N10O9.
What is the molecular weight of Losoxantrone hydrochloride?
The molecular weight of Losoxantrone hydrochloride is 1012.33 g/mol.
Where can I buy Losoxantrone hydrochloride?
You can request a quote for Losoxantrone hydrochloride directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Losoxantrone hydrochloride?
Yes, KEHONG BIO provides custom synthesis services for Losoxantrone hydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.