利福平
TL;DR: 利福平 (CAS 13292-46-1) is a chemical compound with molecular formula C17H16FN3 and molecular weight 281.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
利福平
4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine
Also Known As: 4-(4-fluoronaphthalen-1-yl)-6-isopropylpyrimidin-2-amine, RS 127445 hydrochloride, RS 127445 hydrochloride/, RS-127445 HCl, 2-Pyrimidinamine, 4-(4-fluoro-1-naphthalenyl)-6-(1-methylethyl)-
| Molecular Formula | C17H16FN3 |
|---|---|
| Molecular Weight | 281.13 g/mol |
| LogP | 4.0 |
| Topological Polar Surface Area | 51.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 281.1328 |
| Heavy Atoms | 21 |
| Complexity | 349.0 |
Chemical Identifiers
| CAS Number | 13292-46-1 |
|---|---|
| SMILES | CC(C)C1=NC(=NC(=C1)C2=CC=C(C3=CC=CC=C32)F)N |
| InChIKey | ZZZQXCUPAJFVBN-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
利福平 (CAS 13292-46-1), with molecular formula C17H16FN3 and molecular weight 281.13 g/mol. IUPAC: 4-(4-fluoronaphthalen-1-yl)-6-propan-2-ylpyrimidin-2-amine.
Chemical Property Profile of 利福平
Property Insights of 利福平
The XLogP value of 4.0 indicates that 利福平 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.8 Ų, 利福平 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 利福平 has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 利福平?
The CAS number of 利福平 is 13292-46-1.
What is the molecular formula of 利福平?
The molecular formula of 利福平 is C17H16FN3.
What is the molecular weight of 利福平?
The molecular weight of 利福平 is 281.13 g/mol.
Where can I buy 利福平?
You can request a quote for 利福平 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 利福平?
Yes, KEHONG BIO provides custom synthesis services for 利福平 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.