Hydrotopotecan
TL;DR: Hydrotopotecan (CAS 132877-29-3) is a chemical compound with molecular formula C23H25N3O6 and molecular weight 439.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(2S)-2-[1-[(dimethylamino)methyl]-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid
Also Known As: Hydrotopotecan, Topotecancarboxylic acid, Topotecan acid sodium salt, Topotecan hydroxy acid, HYDROLYZED PRODUCT OF TOPOTECAN
| Molecular Formula | C23H25N3O6 |
|---|---|
| Molecular Weight | 439.17 g/mol |
| LogP | -2.0 |
| Topological Polar Surface Area | 134.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 6 |
| Exact Mass | 439.17435 |
| Heavy Atoms | 32 |
| Complexity | 855.0 |
Chemical Identifiers
| CAS Number | 132877-29-3 |
|---|---|
| SMILES | CC[C@](C1=C(C(=O)N2CC3=CC4=C(C=CC(=C4CN(C)C)O)N=C3C2=C1)CO)(C(=O)O)O |
| InChIKey | DPQJTQJZJNYUEC-QHCPKHFHSA-N |
Product Overview
Hydrotopotecan (CAS 132877-29-3), with molecular formula C23H25N3O6 and molecular weight 439.17 g/mol. IUPAC: (2S)-2-[1-[(dimethylamino)methyl]-2-hydroxy-8-(hydroxymethyl)-9-oxo-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoic acid.
Chemical Property Profile of Hydrotopotecan
Property Insights of Hydrotopotecan
The XLogP value of -2.0 indicates that Hydrotopotecan is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 134.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Hydrotopotecan. Following Lipinski's Rule of Five, Hydrotopotecan has 4 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Hydrotopotecan?
The CAS number of Hydrotopotecan is 132877-29-3.
What is the molecular formula of Hydrotopotecan?
The molecular formula of Hydrotopotecan is C23H25N3O6.
What is the molecular weight of Hydrotopotecan?
The molecular weight of Hydrotopotecan is 439.17 g/mol.
Where can I buy Hydrotopotecan?
You can request a quote for Hydrotopotecan directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Hydrotopotecan?
Yes, KEHONG BIO provides custom synthesis services for Hydrotopotecan and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.