N,O-bis(trimethylsilyl)acetamide structure

N,O-bis(trimethylsilyl)acetamide

TL;DR: N,O-bis(trimethylsilyl)acetamide (CAS 132255-83-5) is a chemical compound with molecular formula C8H21NOSi2 and molecular weight 203.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

trimethylsilyl (1E)-N-trimethylsilylethanimidate

Also Known As: N,O-Bis(trimethylsilyl)acetamide, Bis(trimethylsilyl)acetamide, Dynasylan BSA, BSA?, BSA+TMCS, 5:1

CAS: 132255-83-5
Molecular Formula C8H21NOSi2
Molecular Weight 203.12 g/mol
LogP 3.0912
Topological Polar Surface Area 21.59 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 203.11617
Heavy Atoms 12
Complexity 176.47733

Chemical Identifiers

CAS Number 132255-83-5
SMILES C/C(=N\[Si](C)(C)C)/O[Si](C)(C)C

Product Overview

N,O-bis(trimethylsilyl)acetamide (CAS 132255-83-5), with molecular formula C8H21NOSi2 and molecular weight 203.12 g/mol. IUPAC: trimethylsilyl (1E)-N-trimethylsilylethanimidate.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of N,O-bis(trimethylsilyl)acetamide

XLogP
3.0912
TPSA (Topological Polar Surface Area)
21.59
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
12
Complexity
176.47733
Exact Mass
203.11617
Monoisotopic Mass
203.11617
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N,O-bis(trimethylsilyl)acetamide

The XLogP value of 3.0912 indicates that N,O-bis(trimethylsilyl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 21.59 Ų, N,O-bis(trimethylsilyl)acetamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N,O-bis(trimethylsilyl)acetamide has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N,O-bis(trimethylsilyl)acetamide?

The CAS number of N,O-bis(trimethylsilyl)acetamide is 132255-83-5.

What is the molecular formula of N,O-bis(trimethylsilyl)acetamide?

The molecular formula of N,O-bis(trimethylsilyl)acetamide is C8H21NOSi2.

What is the molecular weight of N,O-bis(trimethylsilyl)acetamide?

The molecular weight of N,O-bis(trimethylsilyl)acetamide is 203.12 g/mol.

Where can I buy N,O-bis(trimethylsilyl)acetamide?

You can request a quote for N,O-bis(trimethylsilyl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N,O-bis(trimethylsilyl)acetamide?

Yes, KEHONG BIO provides custom synthesis services for N,O-bis(trimethylsilyl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

🤖 科弘生物 AI 助手 ×
您好!我是 科弘生物 AI 助手。可以问我产品搜索、询价、样品或技术问题。如何帮助您?